Department of Dermatology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA.
Department of Medicine, University of Toronto, Toronto, ON, Canada.
J Eur Acad Dermatol Venereol. 2016 Jul;30(7):1115-9. doi: 10.1111/jdv.13614. Epub 2016 Mar 10.
In this age of expanding choices of therapy for psoriasis, topical therapies still play an important part in the management of patients. There are many knowledge gaps in topical therapy for psoriasis with regard to efficacy and safety as well as various combinations including topical therapy with phototherapy or with systemic agents. Councillors of the International Psoriasis Council comprised a topical therapy working group to describe these gaps in order to help direct future research endeavours. Herein, we present the results of this analysis, discuss topical agents in clinical development and the attributes of the ideal topical treatment for psoriasis.
在这个治疗银屑病的选择不断扩大的时代,局部治疗仍然在患者管理中发挥着重要作用。在银屑病的局部治疗方面,无论是在疗效和安全性方面,还是在光疗或与全身药物联合治疗方面,都存在许多知识空白。国际银屑病理事会的顾问组成了一个局部治疗工作组,以描述这些空白,以帮助指导未来的研究工作。在此,我们介绍了这项分析的结果,讨论了正在临床开发中的局部治疗药物以及理想的银屑病局部治疗药物的特征。