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Hemolytic vascular inflammation: an update.

作者信息

Conran Nicola, Almeida Camila Bononi

机构信息

Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.

Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE), São Paulo, SP, Brazil.

出版信息

Rev Bras Hematol Hemoter. 2016 Jan-Feb;38(1):55-7. doi: 10.1016/j.bjhh.2015.10.004. Epub 2015 Nov 28.

DOI:10.1016/j.bjhh.2015.10.004
PMID:26969775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4786764/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bb0/4786764/5eb5c83fa94c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bb0/4786764/5eb5c83fa94c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bb0/4786764/5eb5c83fa94c/gr1.jpg

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Intravascular hemolysis triggers ADP-mediated generation of platelet-rich thrombi in precapillary pulmonary arterioles.血管内溶血触发前毛细血管性肺小动脉中 ADP 介导的血小板丰富血栓的形成。
JCI Insight. 2020 Jul 23;5(14):139437. doi: 10.1172/jci.insight.139437.
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Potential therapeutic action of nitrite in sickle cell disease.亚硝酸盐在镰状细胞病中的潜在治疗作用。
Redox Biol. 2017 Aug;12:1026-1039. doi: 10.1016/j.redox.2017.05.006. Epub 2017 May 10.

本文引用的文献

1
Acute hemolytic vascular inflammatory processes are prevented by nitric oxide replacement or a single dose of hydroxyurea.急性溶血性血管炎症过程可通过补充一氧化氮或单次使用羟基脲来预防。
Blood. 2015 Aug 6;126(6):711-20. doi: 10.1182/blood-2014-12-616250. Epub 2015 May 27.
2
Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development.触珠蛋白、血红素结合蛋白及相关防御途径:基础科学、临床观点与药物研发。
Front Physiol. 2014 Oct 28;5:415. doi: 10.3389/fphys.2014.00415. eCollection 2014.
3
Hemolysis-induced lethality involves inflammasome activation by heme.
溶血诱导的致死性涉及血红素对炎性小体的激活。
Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4110-8. doi: 10.1073/pnas.1405023111. Epub 2014 Sep 15.
4
Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease.血红素诱导的中性粒细胞胞外诱捕网导致镰状细胞病的发病机制。
Blood. 2014 Jun 12;123(24):3818-27. doi: 10.1182/blood-2013-10-529982. Epub 2014 Mar 11.
5
Intravascular hemolysis: a disease mechanism not to be ignored.
Acta Haematol. 2014;132(1):97-9. doi: 10.1159/000356836. Epub 2014 Feb 11.
6
Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease.亚铁血红素触发 TLR4 信号通路,导致小鼠镰状细胞病中的内皮细胞激活和血管阻塞。
Blood. 2014 Jan 16;123(3):377-90. doi: 10.1182/blood-2013-04-495887. Epub 2013 Nov 25.
7
Mechanisms of hemolysis-associated platelet activation.溶血相关血小板激活的机制。
J Thromb Haemost. 2013 Dec;11(12):2148-54. doi: 10.1111/jth.12422.
8
Cell-free hemoglobin and its scavenger proteins: new disease models leading the way to targeted therapies.无细胞血红蛋白及其清除蛋白:新的疾病模型引领靶向治疗的发展。
Cold Spring Harb Perspect Med. 2013 Jun 1;3(6):a013433. doi: 10.1101/cshperspect.a013433.
9
Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins.重新探讨溶血和游离血红蛋白:探索血红蛋白和血红素清除剂作为一类新型治疗蛋白。
Blood. 2013 Feb 21;121(8):1276-84. doi: 10.1182/blood-2012-11-451229. Epub 2012 Dec 20.
10
Pulmonary hypertension and nitric oxide depletion in sickle cell disease.镰状细胞病中的肺动脉高压和一氧化氮耗竭。
Blood. 2010 Aug 5;116(5):687-92. doi: 10.1182/blood-2010-02-268193. Epub 2010 Apr 15.