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基于细胞膜包覆的上转换纳米探针用于高特异性肿瘤成像。

Cancer Cell Membrane-Coated Upconversion Nanoprobes for Highly Specific Tumor Imaging.

机构信息

Key Laboratory of Artificial Micro- and Nano-Structuresof Ministry of Education, School of Physics and Technology, Wuhan University, Wuhan, Hubei, 430072, China.

Department of Oral Maxillofacial Head Neck Oncology, School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei, 430079, China.

出版信息

Adv Mater. 2016 May;28(18):3460-6. doi: 10.1002/adma.201506086. Epub 2016 Mar 10.

Abstract

Cancer cell membrane-coated upconversion nanoprobes (CC-UCNPs) with immune escape and homologous targeting capabilities are used for highly specific tumor imaging. The combination of UCNPs with biomimetic cancer cell membranes embodies a novel materials design strategy and presents a compelling class of advanced materials.

摘要

具有免疫逃逸和同源靶向能力的癌细胞膜包覆上转换纳米探针(CC-UCNPs)可用于高度特异性的肿瘤成像。将上转换纳米颗粒与仿生癌细胞膜相结合体现了一种新颖的材料设计策略,并提供了一类引人注目的先进材料。

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