Krumlauf Robb
Stowers Institute for Medical Research, Kansas City, Missouri, USA; Department of Anatomy & Cell Biology, Kansas University Medical School, Kansas City, Kansas, USA.
Curr Top Dev Biol. 2016;116:581-96. doi: 10.1016/bs.ctdb.2015.12.011. Epub 2016 Jan 21.
The hindbrain develops through a process of segmentation which is coupled with the ordered expression of Hox genes to generate regional diversity of key neural and craniofacial derivatives during head development. This is a fundamental feature governed by a gene regulatory network conserved to the base of vertebrate evolution.
后脑通过一个分段过程发育,该过程与Hox基因的有序表达相结合,以在头部发育过程中产生关键神经和颅面衍生物的区域多样性。这是一个由脊椎动物进化基础上保守的基因调控网络控制的基本特征。