Kabuto Miho, Fujimoto Noriki, Hamaguchi Yasuhito, Tanaka Toshihiro
Department of Dermatology, Shiga University of Medical Science, Otsu, Japan.
Department of Dermatology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
J Dermatol. 2016 Aug;43(8):958-61. doi: 10.1111/1346-8138.13344. Epub 2016 Mar 12.
Annular erythema with Sjögren's syndrome (AESS) is occasionally found, especially in Asian patients, which is classified into three types. We present a case of Sjögren's syndrome showing various types of AESS with anti-signal recognition particle antibody-positive polymyositis. We successfully treated the eruption and myositis with a low dose of prednisolone. Every onset of annular erythema coincided with elevation of serum creatine kinase levels, which suggests the correlation between the activities of annular erythema and polymyositis.
伴有干燥综合征的环形红斑(AESS)偶尔会被发现,尤其是在亚洲患者中,它可分为三种类型。我们报告一例干燥综合征患者,其表现为各种类型的AESS并伴有抗信号识别颗粒抗体阳性的多发性肌炎。我们用低剂量泼尼松龙成功治疗了皮疹和肌炎。每次环形红斑发作都与血清肌酸激酶水平升高同时出现,这表明环形红斑和多发性肌炎的活动之间存在相关性。