Virapongse C, Brown E, Malat J
University of Florida, Gainesville.
Top Magn Reson Imaging. 1989 Dec;2(1):63-75.
The sensitivity of MRI to changes in water state and volume makes it the most desirable modality for imaging early brain ischemia. Its sensitivity is reflected in the ability to show ischemic changes in the white matter of the asymptomatic elderly, which are attributed to axonal loss, demyelination, and gliosis. In large infarcts, however, contrast enhancement with Gd-DTPA can be used to add specificity, should doubt exist as to the proper diagnosis. The ability of MR to image flow is a valuable adjunct, and MR angiography has the potential partially to replace invasive angiography. Applications of MR such as diffusion-perfusion studies, sodium imaging, and spectroscopy could all prove to be useful in the future.
MRI对水状态和体积变化的敏感性使其成为早期脑缺血成像最理想的方式。其敏感性体现在能够显示无症状老年人白质中的缺血性变化，这些变化归因于轴突丢失、脱髓鞘和神经胶质增生。然而，在大面积梗死中，如果对正确诊断存在疑问，使用钆喷酸葡胺（Gd-DTPA）进行对比增强可增加诊断的特异性。磁共振成像血流的能力是一项有价值的辅助手段，磁共振血管造影有可能部分取代有创血管造影。诸如弥散灌注研究、钠成像和波谱分析等磁共振应用在未来都可能被证明是有用的。
