Hesselink J R, Press G A
University of California School of Medicine, San Diego.
Radiol Clin North Am. 1988 Jul;26(4):873-87.
Gd-DTPA is a paramagnetic contrast agent for MR that produces enhancement of lesions on T1-weighted images. Since it does not cross the intact blood-brain barrier (BBB), Gd-DTPA enhances only those pathologic processes that are associated with breakdown of the BBB and structures or lesions that are devoid of a BBB. Gd-DTPA improves conspicuity, helps characterize and delineate the extent of lesions, and increases the sensitivity for detection of cerebral abnormalities.
钆喷酸葡胺是一种用于磁共振成像的顺磁性造影剂，可使T1加权图像上的病变增强。由于它不能穿过完整的血脑屏障（BBB），钆喷酸葡胺仅能增强那些与血脑屏障破坏相关的病理过程以及缺乏血脑屏障的结构或病变。钆喷酸葡胺可提高病变的清晰度，有助于对病变进行特征性描述并勾勒其范围，还能提高检测脑部异常的敏感性。
