From the *Department of Nuclear Medicine, Peking University First Hospital; †Department of Nuclear Medicine, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China; and ‡Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Clin Nucl Med. 2016 Jul;41(7):578-9. doi: 10.1097/RLU.0000000000001207.
Mast cell leukemia (MCL) is a very rare subtype of systemic mastocytosis, characterized by the leukemic expansion of immature mast cells. We present a case of MCL with extramedullary involvement of cervical lymph node and lung demonstrated by the initial F-FDG PET/CT scan. After a transient complete remission by induction chemotherapy and allogeneic hematopoietic stem cell transplantation, the follow-up PET/CT showed extensive extramedullary relapse involving multiple lymph nodes and small bowel. F-FDG PET/CT may be a useful tool to comprehensively stage and follow-up MCL.
肥大细胞白血病（MCL）是一种非常罕见的系统性肥大细胞增多症的亚型，其特征是不成熟的肥大细胞白血病样扩展。我们报告了一例 MCL 病例，其初始 F-FDG PET/CT 扫描显示颈部淋巴结和肺部有髓外累及。经诱导化疗和异基因造血干细胞移植后短暂完全缓解后，随访 PET/CT 显示广泛的髓外复发累及多个淋巴结和小肠。F-FDG PET/CT 可能是全面分期和随访 MCL 的有用工具。
