Carmona-Sánchez R, Icaza-Chávez M E, Bielsa-Fernández M V, Gómez-Escudero O, Bosques-Padilla F, Coss-Adame E, Esquivel-Ayanegui F, Flores-Rendón Á R, González-Martínez M A, Huerta-Iga F, López-Colombo A, Méndez-Gutiérrez T H, Noble-Lugo A, Nogueira-de Rojas J R, Raña-Garibay R H, Remes-Troche J M, Roesch-Dietlen F, Schmulson M J, Soto-Pérez J C, Tamayo J L, Uscanga L F, Valdovinos M Á, Valerio-Ureña J, Zavala-Solares M R
Práctica privada, San Luis Potosí, S.L.P., México.
Hospital Star Médica de Mérida, Mérida, Yucatán, México.
Rev Gastroenterol Mex. 2016 Jul-Sep;81(3):149-67. doi: 10.1016/j.rgmx.2016.01.004. Epub 2016 Mar 11.
Since the publication in 2009 of the Guidelines on the Diagnosis and Treatment of Irritable Bowel Syndrome of the Asociación Mexicana de Gastroenterología (2009 Guidelines), there have been significant advances in our knowledge of the epidemiology, pathophysiology, diagnosis, and treatment of this disease.
To present a consensus review of the most current knowledge of IBS, updating the 2009 Guidelines by incorporating new internationally published scientific evidence, with a special interest in Mexican studies.
The PubMed literature from January 2009 to March 2015 was reviewed and complemented through a manual search. Articles in English and Spanish were included and preference was given to consensuses, guidelines, systematic reviews, and meta-analyses. Statements referring to the different aspects of the disease were formulated and voted upon by 24 gastroenterologists employing the Delphi method. Once a consensus on each statement was reached, the quality of evidence and strength of recommendation were determined through the GRADE system.
Forty-eight statements were formulated, updating the information on IBS and adding the complementary data that did not appear in the 2009 Guidelines regarding the importance of exercise and diet, diagnostic strategies, and current therapy alternatives that were analyzed with more stringent scientific vigor or that emerged within the last 5 years.
We present herein a consensus review of the most relevant advances in the study of IBS, updating and complementing the 2009 Guidelines. Several studies conducted in Mexico were included.
自墨西哥胃肠病学协会《肠易激综合征诊断和治疗指南》（2009年指南）于2009年发布以来，我们对该疾病的流行病学、病理生理学、诊断和治疗的认识有了显著进展。
对肠易激综合征的最新知识进行共识性综述，通过纳入新的国际发表的科学证据更新2009年指南，特别关注墨西哥的研究。
对2009年1月至2015年3月的PubMed文献进行综述，并通过手工检索进行补充。纳入英文和西班牙文的文章，优先选择共识、指南、系统评价和荟萃分析。由24位胃肠病学家采用德尔菲法制定并投票表决关于该疾病不同方面的陈述。一旦就每项陈述达成共识，通过GRADE系统确定证据质量和推荐强度。
制定了48项陈述，更新了关于肠易激综合征的信息，并添加了2009年指南中未出现的补充数据，涉及运动和饮食的重要性、诊断策略以及当前的治疗选择，这些内容以更严格的科学活力进行了分析或在过去5年内出现。
我们在此呈现对肠易激综合征研究中最相关进展的共识性综述，更新并补充了2009年指南。纳入了在墨西哥进行的多项研究。
