Fuller-Thomson Esme, Hollister Bailey
Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, ON, Canada M5S 1V4.
Schizophr Res Treatment. 2016;2016:3165243. doi: 10.1155/2016/3165243. Epub 2016 Feb 10.
This study examined factors associated with suicide attempts among those with schizophrenia (n = 101) versus those without (n = 21,643) in a representative sample of noninstitutionalized Canadians. The lifetime prevalence of suicide attempts among persons with schizophrenia was 39.2% versus 2.8% of nonafflicted individuals. After adjusting for sociodemographics, childhood adversities, substance abuse/dependence, depression/anxiety, and chronic pain, those with schizophrenia had 6 times the odds (OR = 6.47) of attempting suicide. Among persons with schizophrenia, suicide attempts were associated with female gender (OR = 4.59), substance abuse/dependence (OR = 6.31), depression (OR = 4.93), and childhood physical abuse (OR = 5.75). Community-dwelling persons with schizophrenia appear to be at high risk for suicide attempts.
本研究在加拿大非机构化人群的代表性样本中，调查了精神分裂症患者（n = 101）与非精神分裂症患者（n = 21,643）中与自杀未遂相关的因素。精神分裂症患者的终身自杀未遂患病率为39.2%，而非患病个体为2.8%。在调整社会人口统计学、童年逆境、药物滥用/依赖、抑郁/焦虑和慢性疼痛因素后，精神分裂症患者自杀未遂的几率是常人的6倍（OR = 6.47）。在精神分裂症患者中，自杀未遂与女性性别（OR = 4.59）、药物滥用/依赖（OR = 6.31）、抑郁（OR = 4.93）和童年身体虐待（OR = 5.75）相关。社区居住的精神分裂症患者似乎有很高的自杀未遂风险。
