成人与儿童脊髓内肿瘤的比较流行病学
Comparative epidemiology of adult and pediatric intramedullary spinal cord tumors.
作者信息
Kushel Yu V, Belova Yu D
机构信息
Burdenko Neurosurgical Institute, Moscow, Russia.
出版信息
Zh Vopr Neirokhir Im N N Burdenko. 2015;79(6):22-28. doi: 10.17116/neiro201579622-28.
UNLABELLED
Intramedullary spinal cord tumors (IMSCTs) are a rare pathology. They can be found at any age. Our experience with more than 507 surgeries for IMSCTs revealed some differences between pediatric and adult IMSCTs.
AIM
We used a large surgical series to conduct comparative analysis of the main epidemiological characteristics of intramedullary tumors in children and adults and to identify possible differences.
MATERIAL AND METHODS
Prospectively collected data from 224 pediatric and 242 adult patients operated by one surgeon (YK) for last 12 years were analyzed.
RESULTS
Pediatric IMSCTs are more extensive and children undergo treatment in worse clinical condition than adults. There are age-related differences in the tumor localization. The astrocytoma/ependymoma ratio was 83/17 in children and 21/79 in adults.
CONCLUSION
We confirmed differences in IMSCTs in different age groups. Late diagnosis is a problem in the pediatric subgroup of IMSCT patients.
未标注
脊髓髓内肿瘤（IMSCTs）是一种罕见的病理情况。可在任何年龄发现。我们对507多例脊髓髓内肿瘤手术的经验揭示了儿童和成人脊髓髓内肿瘤之间的一些差异。
目的
我们使用一个大型手术系列对儿童和成人髓内肿瘤的主要流行病学特征进行比较分析，并确定可能存在的差异。
材料与方法
分析了由一名外科医生（YK）在过去12年中对224例儿童和242例成人患者进行手术时前瞻性收集的数据。
结果
儿童脊髓髓内肿瘤范围更广，且与成人相比，儿童接受治疗时的临床状况更差。肿瘤定位存在与年龄相关的差异。儿童星形细胞瘤/室管膜瘤的比例为83/17，成人为21/79。
结论
我们证实了不同年龄组脊髓髓内肿瘤存在差异。在脊髓髓内肿瘤患者的儿童亚组中，诊断延迟是一个问题。
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