Banerji Aleena, Riedl Marc
Massachusetts General Hospital, Cox 201, 55 Fruit Street, Boston, MA, USA.
University of California, San Diego, La Jolla, CA, USA.
Womens Health (Lond). 2016 Jun;12(3):351-61. doi: 10.2217/whe.16.6. Epub 2016 Mar 15.
Hereditary angioedema (HAE) is a rare disorder resulting from decreased functional levels of C1-inhibitor (C1-INH), which manifests as periodic episodes of localized edema which can be extremely painful, debilitating and even fatal if the swelling affects the larynx. HAE can complicate many aspects of obstetric/gynecologic care, and an awareness of the disease is critical for clinicians involved in the care of women because of potential HAE-related complications pertaining to pregnancy, labor and delivery, and other women's health issues. This article provides a review of published literature specific to HAE and its management in female patients, including important concerns regarding obstetric/gynecologic care. A growing body of relevant experience is presented to help guide the care of women with HAE.
遗传性血管性水肿（HAE）是一种罕见的疾病，由C1抑制剂（C1-INH）功能水平降低引起，表现为局部水肿的周期性发作，如果肿胀影响喉部，可能会极其疼痛、使人衰弱甚至致命。HAE会使产科/妇科护理的许多方面变得复杂，对于参与女性护理的临床医生来说，了解这种疾病至关重要，因为与HAE相关的潜在并发症涉及妊娠、分娩和其他女性健康问题。本文综述了关于HAE及其在女性患者中的管理的已发表文献，包括与产科/妇科护理相关的重要问题。本文还介绍了越来越多的相关经验，以帮助指导HAE女性患者的护理。
