Inhibition of Histone Demethylases Offers a Novel and Promising Approach for the Treatment of Cancer and Other Diseases.
作者信息
Abdel-Magid Ahmed F
机构信息
Therachem Research Medilab (India) Pvt. Ltd. , Jaipur, India.
出版信息
ACS Med Chem Lett. 2015 Dec 1;7(2):128-30. doi: 10.1021/acsmedchemlett.5b00437. eCollection 2016 Feb 11.
Abstract
摘要
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本文引用的文献
1
Histone methylases as novel drug targets: developing inhibitors of EZH2.组蛋白甲基化酶作为新型药物靶点：开发EZH2抑制剂
Future Med Chem. 2014;6(17):1943-65. doi: 10.4155/fmc.14.123.
2
Histone lysine demethylases as targets for anticancer therapy.组蛋白赖氨酸去甲基化酶作为抗癌治疗的靶点。
Nat Rev Drug Discov. 2013 Dec;12(12):917-30. doi: 10.1038/nrd4154. Epub 2013 Nov 15.
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Chromatin proteins and modifications as drug targets.染色质蛋白和修饰作为药物靶点。
Nature. 2013 Oct 24;502(7472):480-8. doi: 10.1038/nature12751.
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Small molecule epigenetic inhibitors targeted to histone lysine methyltransferases and demethylases.针对组蛋白赖氨酸甲基转移酶和去甲基化酶的小分子表观遗传抑制剂。
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