Hallmann-Szelińska E, Bednarska K, Kondratiuk K, Rabczenko D, Brydak L B
Department of Influenza Research, National Influenza Centre, National Institute of Public Health - National Institute of Hygiene, 24 Chocimska St., 00-791, Warsaw, Poland.
Centre of Monitoring and Analyses of Population Health Status, National Institute of Public Health - National Institute of Hygiene, 24 Chocimska St., 00-791, Warsaw, Poland.
Adv Exp Med Biol. 2016;912:51-6. doi: 10.1007/5584_2016_209.
In every epidemic season, viral infections affect the general population, including children, which is an underestimated issue. The present study demonstrates the results of examination of 802 clinical samples obtained from pediatric patients aged 0-14 years during the 2014/2015 epidemic season in Poland. The study was part of the virological surveillance systems - SENTINEL and NON-SENTINEL. A positive result for virological infection was obtained in 50.9 % of samples tested. The distribution of positive results by the age-groups was as follows: 38.2 % in 0-4 years old, 8.5 % in 5-9 years old, and 4.2 % in 10-14 years old children. Influenza viruses accounted for 48.0 % and influenza-like viruses for 52.0 % of all positive samples. Concerning the influenza virus, molecular biology-based techniques confirmed the infection caused by influenza type A in 63.3 % of samples, consisting of unsubtyped A virus detected in 65.3 % of cases of this sample group, subtype A/H1N1/pdm09 in 28.2 %, and subtype A/H3N2/ in 6.5 %. Genetic material of influenza B was detected in 36.7 % of samples. In a group of influenza-like viruses, the predominant virus was respiratory syncytial virus (RSV) in as many as 96.2 % of samples, followed by parainfluenza viruses: PIV3 - 1.4 % and PIV1 - 1.0 %. Attention should be paid to the coinfection of respiratory viruses. There were six possible coinfection combinations reported in Poland, with four of them related to children up to 14 years old.
在每个流行季节，病毒感染都会影响包括儿童在内的普通人群，这是一个被低估的问题。本研究展示了对2014/2015年波兰流行季节从0至14岁儿科患者获取的802份临床样本进行检测的结果。该研究是病毒学监测系统——哨兵系统和非哨兵系统的一部分。在所检测的样本中，50.9%获得了病毒学感染阳性结果。按年龄组划分的阳性结果分布如下：0至4岁儿童中为38.2%，5至9岁儿童中为8.5%，10至14岁儿童中为4.2%。流感病毒占所有阳性样本的48.0%，类流感病毒占52.0%。关于流感病毒，基于分子生物学的技术在63.3%的样本中证实为甲型流感病毒感染，其中该样本组65.3%的病例检测到未分型甲型病毒，28.2%为甲型H1N1/pdm09亚型，6.5%为甲型H3N2亚型。36.7%的样本中检测到乙型流感病毒的遗传物质。在类流感病毒组中，占主导地位的病毒是呼吸道合胞病毒（RSV），在多达96.2%的样本中存在，其次是副流感病毒：副流感病毒3型（PIV3）——1.4%，副流感病毒1型（PIV1）——1.0%。应关注呼吸道病毒的合并感染。波兰报告了六种可能的合并感染组合，其中四种与14岁以下儿童有关。
