Scholtissen B, Dijkstra J, Reithler J, Leentjens A F G
1Institute of Brain and Behavior, Maastricht University, Maastricht, The Netherlands.
2Department of Psychiatry, Maastricht University Hospital, Maastricht, The Netherlands.
Acta Neuropsychiatr. 2006 Feb;18(1):38-41. doi: 10.1111/j.0924-2708.2006.00122.x.
Patients suffering from Parkinson's disease (PD) are often reported to have an impaired performance on tests measuring executive functioning, such as fluency tasks.
To investigate whether verbal fluency is impaired in PD patients (n = 25) compared with healthy controls (n = 15) using a 2-min semantic and phonemic verbal fluency test. A 2-min version of the fluency task was used to allow for more switches between clusters to study retrieval strategies more adequately.
No differences in performance on both semantic and phonemic fluency tasks between the PD patients and the control persons were found. Moreover, both groups appeared to use the same retrieval strategies.
Patients suffering from PD appear to use the same strategies for producing words as healthy controls do. Different pathways may be involved in switching clusters during the fluency task than in other types of switching that may be impaired in PD, such as motor switching and concept-shifting.
据报道，帕金森病（PD）患者在执行功能测试（如流畅性任务）中的表现往往受损。
使用2分钟的语义和音素言语流畅性测试，调查与健康对照者（n = 15）相比，PD患者（n = 25）的言语流畅性是否受损。使用2分钟版本的流畅性任务，以便在不同类别之间有更多切换，从而更充分地研究检索策略。
在PD患者和对照者之间，语义和音素流畅性任务的表现没有差异。此外，两组似乎使用相同的检索策略。
PD患者产生单词的策略似乎与健康对照者相同。在流畅性任务中切换类别可能涉及与PD中可能受损的其他类型切换（如运动切换和概念转换）不同的途径。
