Physical Therapy, Occupational Therapy and Speech Therapy Department, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil.
ReMove, Rehabilitation in Movement Disorders Research Group, University of São Paulo, São Paulo, SP, Brazil.
Biomed Res Int. 2017;2017:7893975. doi: 10.1155/2017/7893975. Epub 2017 Aug 20.
Executive function deficits are observed in people with Parkinson's disease (PD) from early stages and have great impact on daily living activities. Verbal fluency and oral diadochokinesia involve phonarticulatory coordination, response inhibition, and phonological processing and may also be affected in people with PD. This study aimed to describe the performance of PD patients and an age- and education-matched control group on executive function, verbal fluency, and oral diadochokinesia tests and to investigate possible relationships between them.
Forty people with PD and forty controls were evaluated with Trail Making Test (TMT, executive function) and phonemic/semantic verbal fluency and oral diadochokinesia (/pataka/) tests. Groups were compared by ANOVA and relationships were investigated by Pearson tests.
People with PD showed longer times in parts A and B of TMT. They also said fewer words in phonemic/semantic verbal fluency tests and less syllables in the diadochokinesia test. Oral diadochokinesia strongly correlated to parts A and B of TMT and to phonemic verbal fluency.
Oral diadochokinesia was correlated to executive function and verbal fluency. The cognitive-motor interaction in verbal fluency and oral diadochokinesia must be considered not to overestimate the cognitive or motor impairments in people with PD.
执行功能缺陷在帕金森病（PD）患者的早期阶段就已经观察到，对日常生活活动有很大的影响。言语流畅性和口头交替流畅性涉及语音协调、反应抑制和语音处理，也可能受到 PD 患者的影响。本研究旨在描述 PD 患者和年龄、教育相匹配的对照组在执行功能、言语流畅性和口头交替流畅性测试中的表现，并探讨它们之间的可能关系。
40 名 PD 患者和 40 名对照组接受了连线测试（TMT，执行功能）和语音/语义言语流畅性和口头交替流畅性（/pataka/）测试。通过方差分析比较组间差异，通过皮尔逊检验探讨相关性。
PD 患者在 TMT 的 A 部分和 B 部分用时较长。他们在语音/语义言语流畅性测试中也说出的单词较少，在交替流畅性测试中说出的音节较少。口头交替流畅性与 TMT 的 A 部分和 B 部分以及语音言语流畅性高度相关。
口头交替流畅性与执行功能和言语流畅性相关。在言语流畅性和口头交替流畅性中，认知-运动的相互作用必须被考虑，以免过高估计 PD 患者的认知或运动障碍。
