茉莉酮及一些类似化合物的体外抗真菌作用。构效关系
[Antifungal effects in vitro of jasmon and some similar compounds. Structure-activity relationship].
作者信息
Millet-Clerc J, Michel D, Chaumont J P
出版信息
Ann Pharm Fr. 1989;47(3):157-61.
PMID:2699545
Abstract
The antimycotic activity in vitro of jasmon and 6 closely related substances has been tested against four different dermatophytes, Candida albicans, Pityrosporum ovale and Aspergillus fumigatus. Jasmon had the highest activity. Among the other substances tested only thiazolidines with a carbonyl function developed antifungal properties against dermatophytes. 2,4 thiazolidinedione at 450 ppm inhibits the growth of Trichophyton rubrum.
摘要
已测试茉莉酮及6种密切相关物质对4种不同皮肤真菌、白色念珠菌、卵形糠秕孢子菌和烟曲霉的体外抗真菌活性。茉莉酮具有最高活性。在测试的其他物质中，只有具有羰基功能的噻唑烷对皮肤真菌产生了抗真菌特性。450 ppm的2,4-噻唑烷二酮可抑制红色毛癣菌的生长。
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