Archambault F, Durand G, Faivre J, Voilquin J P, Archambault P, Riou F, Ageorges P, Archambault M L, Delville J M, Fesneau M
Association Médicale de Formation Médicale Continue, Neuville-aux-Bois, France.
Bull Cancer. 1989;76(10):1071-5.
In view of preparing a controlled trial to assess the efficacy of screening for colorectal cancer by fecal occult blood testing in reducing cancer mortality, a pilot study was performed to evaluate the acceptability rate of the Hemoccult test in non selected subjects consulting in a general practice. 566 subjects aged 45 to 74 years from two small towns, Neuville-aux-Bois (Loiret) and Vicherey (Vosges) were included in the study. The screening test was proposed by GPs to 89.2% of their patients; of these, 5.6% refused the test and 9.4% did not return it. Of the tests carried out, 80.8% were performed spontaneously, and 19.2% after a recall letter. Acceptability depended neither on age or on sex. The patients' confidence in his GP was the most important acceptability factor (60%), followed by explanations the GP had provided, and ease of application. The results suggest that after receiving the correct information, a GP will succeed in prescribing the Hemoccult test to most high-risk subjects and that acceptability then proves excellent. Experience drawn from the pilot study has been very useful in conceiving the on-going controlled trial in Burgundy.
鉴于准备开展一项对照试验以评估粪便潜血试验筛查结直肠癌在降低癌症死亡率方面的疗效,进行了一项试点研究,以评估在普通诊所就诊的未选定受试者中隐血试验的接受率。来自两个小镇——卢瓦雷省的讷维勒-奥布瓦和孚日省的维谢雷——的566名45至74岁的受试者被纳入研究。全科医生向89.2%的患者提议进行筛查试验;其中,5.6%的患者拒绝了该试验,9.4%的患者未归还试验样本。在进行的试验中,80.8%是患者自发进行的,19.2%是在收到召回信后进行的。接受率既不取决于年龄也不取决于性别。患者对其全科医生的信任是最重要的接受因素(60%),其次是全科医生提供的解释以及应用的便利性。结果表明,在获得正确信息后,全科医生将成功地为大多数高危受试者开具隐血试验,并且接受率随后被证明非常高。从试点研究中汲取的经验对于构思正在勃艮第进行的对照试验非常有用。