准分子激光原位角膜磨镶术后压力性基质性角膜病变的药物治疗

Pharmacologic Management of Pressure-Induced Stromal Keratopathy after LASIK.

作者信息

Unlu Metin, Hondur Ahmet M, Korkmaz Safak, Kumova Deniz, Yuksel Erdem

机构信息

*MD Department of Ophthalmology, School of Medicine (MU), Erciyes University, Kayseri, Turkey; Department of Ophthalmology, School of Medicine (AMH, EY), Gazi University, Ankara, Turkey; Department of Ophthalmology (SK), Duzici State Hospital, Duzici, Turkey; and Department of Ophthalmology (DK), Viransehir State Hospital, Sanliurfa, Turkey.

出版信息

Optom Vis Sci. 2016 Jul;93(7):757-9. doi: 10.1097/OPX.0000000000000853.

DOI:10.1097/OPX.0000000000000853

PMID:27003814

Abstract

PURPOSE

To emphasize the importance of anticipation of pressure-induced stromal keratopathy (PISK) in eyes with a previous history of LASIK.

CASE REPORT

A 40-year-old man developed LASIK-related pressure-induced stromal keratopathy after uneventful phacoemulsification (Phaco) and intraocular lens (IOL) implantation in his left eye. With immediate discontinuation of the steroid drops and initiation of antiglaucoma medication, his visual acuity, interface edema, and haze improved rapidly. One year later, during Phaco with IOL implantation in his other eye, with anticipation of a similar LASIK-related pressure-induced stromal keratopathy, a very brief course of soft steroid therapy was given together with antiglaucoma medication. Intraocular pressure elevation was avoided, and no interface edema or haze was observed.

CONCLUSIONS

This case illustrates that the risk for LASIK-related pressure-induced stromal keratopathy may be reduced with appropriate precautions.

摘要

目的

强调对于有准分子激光原位角膜磨镶术（LASIK）既往史的眼睛，预判压力诱导性基质性角膜病变（PISK）的重要性。

病例报告

一名40岁男性在左眼顺利完成白内障超声乳化吸除术（Phaco）及人工晶状体（IOL）植入术后，发生了与LASIK相关的压力诱导性基质性角膜病变。立即停用类固醇滴眼液并开始使用抗青光眼药物后，他的视力、界面水肿及角膜混浊迅速改善。一年后，在他另一只眼进行Phaco及IOL植入手术时，由于预判会发生类似的与LASIK相关的压力诱导性基质性角膜病变，在使用抗青光眼药物的同时给予了非常短暂疗程的软性类固醇治疗。避免了眼压升高，且未观察到界面水肿或角膜混浊。