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[痴呆症心理社会干预措施的评估:从考科蓝图书馆能学到什么?]

[Evaluation of psychosocial interventions for dementia: what to learn from the Cochrane Library?].

作者信息

Charras Kevin, Gzil Fabrice, Reintjens Christophe, Frémontier Michèle

机构信息

Fondation Médéric Alzheimer, Paris, France.

出版信息

Geriatr Psychol Neuropsychiatr Vieil. 2016 Mar;14(1):104-14. doi: 10.1684/pnv.2016.0593.

Abstract

Psychosocial interventions for people with dementia have expanded in the last decades, and have been subject to an important number of evaluation attempts that often lead to scientifically flaw results. To study these failures we analysed the meta-analyses of the Cochrane Library. Among 18 meta-analyses, 11 were selected for the purpose of this study. These papers were analysed on the basis of the Cochrane selection criteria, methodological quality and biases, principal outcomes and implication for practice and research. Results are discussed and analysed according to the clinical practice and scientific literature of the matter of concern. Main outcomes of this review point that: (1) it is necessary to adopt an investigation methodology adapted to specific characteristics of psychosocial interventions; (2) methodological weaknesses of randomised control trials are prejudicial to quality of research and clinical practice; (3) implementation of randomised control trials call for necessary fundamental prerequisites; and (4) other research methods than randomised control trials are susceptible to give as much, if not more, informative results. A research and practice implementation strategy is suggested.

摘要

在过去几十年中,针对痴呆症患者的心理社会干预措施有所增加,并且受到了大量评估尝试的检验,这些评估往往得出存在科学缺陷的结果。为了研究这些失败案例,我们分析了考科蓝图书馆(Cochrane Library)的荟萃分析。在18项荟萃分析中,有11项被选用于本研究。这些论文根据考科蓝的选择标准、方法学质量和偏差、主要结果以及对实践和研究的启示进行了分析。根据所关注问题的临床实践和科学文献对结果进行了讨论和分析。本综述的主要结果表明:(1)有必要采用适合心理社会干预特定特征的调查方法;(2)随机对照试验的方法学弱点对研究质量和临床实践有害;(3)随机对照试验的实施需要必要的基本前提条件;(4)除随机对照试验之外的其他研究方法有可能给出同样多(甚至更多)的信息性结果。本文提出了一种研究和实践实施策略。

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