Li You, Qin Jian, Wei Xiao, Li Chunhong, Wang Jian, Jiang Meiyu, Liang Xue, Xia Tianlong, Zhang Zhiyong
Department of Occupational and Environmental Health, School of Public Health, Guangxi Medical University, Shuangyong Road No.22, Nanning 530021, China.
Int J Environ Res Public Health. 2016 Mar 8;13(3):296. doi: 10.3390/ijerph13030296.
To investigate the risk factors of child lead poisoning in China.
A document retrieval was performed using MeSH (Medical subject heading terms) and key words. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of the studies, and the pooled odd ratios with a 95% confidence interval were used to identify the risk factors. We employed Review Manager 5.2 and Stata 10.0 to analyze the data. Heterogeneity was assessed by both the Chi-square and I² tests, and publication bias was evaluated using a funnel plot and Egger's test.
Thirty-four articles reporting 13,587 lead-poisoned children met the inclusion criteria. Unhealthy lifestyle and behaviors, environmental pollution around the home and potential for parents' occupational exposure to lead were risk factors of child lead poisoning in the pooled analyses. Our assessments yielded no severe publication biases.
Seventeen risk factors are associated with child lead poisoning, which can be used to identify high-risk children. Health education and promotion campaigns should be designed in order to minimize or prevent child lead poisoning in China.
调查中国儿童铅中毒的危险因素。
使用医学主题词表（MeSH）和关键词进行文献检索。采用纽卡斯尔-渥太华量表（NOS）评估研究质量，并使用合并比值比及95%置信区间来确定危险因素。我们使用Review Manager 5.2和Stata 10.0进行数据分析。通过卡方检验和I²检验评估异质性，并使用漏斗图和Egger检验评估发表偏倚。
34篇报道13587名铅中毒儿童的文章符合纳入标准。在汇总分析中，不健康的生活方式和行为、家庭周围环境污染以及父母职业性铅暴露可能性是儿童铅中毒的危险因素。我们的评估未发现严重的发表偏倚。
17种危险因素与儿童铅中毒相关，可用于识别高危儿童。应开展健康教育和促进活动，以尽量减少或预防中国儿童铅中毒。
