Maurri S, Lambruschini P, Barontini F
Dipartimento di Scienze Neurologiche e Psichiatriche, Università, Firenze.
Riv Neurol. 1989 Nov-Dec;59(6):211-6.
A 63-year-old man suddenly fell in a state of apparent coma. An electroencephalogram (EEG) performed at a local hospital revealed the maintenance of a reactive alpha rhythm over the posterior regions of the scalp, allowing a diagnosis of alert coma. The persistence of minimal degrees of alertness and ability to communicate made the clinical picture classifiable as a "locked-in" syndrome (LIS). Bilateral ptosis and complete ophthalmoplegia oriented towards a total mesencephalic form of LIS. Computed tomography (CT) and magnetic resonance imaging (MRI) of the brain showed pathological findings at mesencephalic level. Such findings were insufficient to explain the clinical picture.
一名63岁男性突然陷入明显昏迷状态。当地医院进行的脑电图（EEG）显示头皮后部区域存在反应性α节律，可诊断为警觉性昏迷。存在最低程度的警觉性和沟通能力，使临床表现可归类为“闭锁综合征”（LIS）。双侧上睑下垂和完全性眼肌麻痹提示为完全性中脑型LIS。脑部计算机断层扫描（CT）和磁共振成像（MRI）显示中脑水平有病理改变。这些发现不足以解释临床表现。
