Farage Filho M, Gomes M D
Arq Neuropsiquiatr. 1982 Sep;40(3):296-300.
The case of a 46 year-old man who had a locked-in syndrome is reported. The patient had a haemorragic vascular accident with tetraplegia, anartria, vertical ocular movements and preservation of the consciousness. The EEG showed a projected disturbance possibly caused by a brain-stem lesion, that was confirmed by the CAT SCAN. Cerebral angiography showed high level of aterosclerosis. The lesion is located in the ventral part of the pons above the nucleus of the abducent nerve, without damaging the substantia reticularis of the mesencephalon and can be caused by thrombosis of the basilar artery and tumor, myastenia gravis, polyneurites, heroin overdose, after swine-flu inoculation and post-infectious polyneurites. The patient is still alive 2 years after the stroke with a good recovery. He can walk and speak fluently, but with cordonal ataxy of the limbs.
报告了一例患有闭锁综合征的46岁男性病例。患者发生出血性脑血管意外，导致四肢瘫痪、无动性缄默、垂直眼球运动存在且意识保留。脑电图显示可能由脑干病变引起的投射性障碍，计算机断层扫描证实了这一点。脑血管造影显示动脉粥样硬化程度较高。病变位于展神经核上方的脑桥腹侧，未损伤中脑网状结构，可由基底动脉血栓形成、肿瘤、重症肌无力、多神经炎、海洛因过量、猪流感接种后以及感染后多神经炎引起。中风两年后患者仍存活，恢复良好。他能够行走且说话流利，但肢体有共济失调。
