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神经工程与神经技术新视角:美国国家科学基金会-德国研究基金会研讨会报告

New Perspectives on Neuroengineering and Neurotechnologies: NSF-DFG Workshop Report.

作者信息

Moritz Chet T, Ruther Patrick, Goering Sara, Stett Alfred, Ball Tonio, Burgard Wolfram, Chudler Eric H, Rao Rajesh P N

出版信息

IEEE Trans Biomed Eng. 2016 Jul;63(7):1354-67. doi: 10.1109/TBME.2016.2543662. Epub 2016 Mar 17.

Abstract

GOAL

To identify and overcome barriers to creating new neurotechnologies capable of restoring both motor and sensory function in individuals with neurological conditions.

METHODS

This report builds upon the outcomes of a joint workshop between the US National Science Foundation and the German Research Foundation on New Perspectives in Neuroengineering and Neurotechnology convened in Arlington, VA, USA, November 13-14, 2014.

RESULTS

The participants identified key technological challenges for recording and manipulating neural activity, decoding, and interpreting brain data in the presence of plasticity, and early considerations of ethical and social issues pertinent to the adoption of neurotechnologies.

CONCLUSIONS

The envisaged progress in neuroengineering requires tightly integrated hardware and signal processing efforts, advances in understanding of physiological adaptations to closed-loop interactions with neural devices, and an open dialog with stakeholders and potential end-users of neurotechnology.

SIGNIFICANCE

The development of new neurotechnologies (e.g., bidirectional brain-computer interfaces) could significantly improve the quality of life of people living with the effects of brain or spinal cord injury, or other neurodegenerative diseases. Focused efforts aimed at overcoming the remaining barriers at the electrode tissue interface, developing implantable hardware with on-board computation, and refining stimulation methods to precisely activate neural tissue will advance both our understanding of brain function and our ability to treat currently intractable disorders of the nervous system.

摘要

目标

识别并克服在开发能够恢复神经疾病患者运动和感觉功能的新型神经技术过程中所面临的障碍。

方法

本报告基于美国国家科学基金会和德国研究基金会于2014年11月13日至14日在美国弗吉尼亚州阿灵顿召开的神经工程与神经技术新视角联合研讨会的成果。

结果

参与者确定了在可塑性存在的情况下记录和操纵神经活动、解码和解释大脑数据的关键技术挑战,以及与采用神经技术相关的伦理和社会问题的早期考量。

结论

神经工程领域预期的进展需要紧密整合硬件和信号处理工作,在理解生理对与神经装置闭环交互的适应性方面取得进展,并与神经技术的利益相关者和潜在最终用户进行开放对话。

意义

新型神经技术(如双向脑机接口)的开发可显著改善因脑或脊髓损伤或其他神经退行性疾病而受影响的人们的生活质量。致力于克服电极组织界面的剩余障碍、开发具有板载计算功能的可植入硬件以及完善刺激方法以精确激活神经组织的集中努力,将推动我们对脑功能的理解以及治疗当前难以治愈的神经系统疾病的能力。

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