Environmental Health Program, Research Centre, King Faisal Specialist Hospital and Research Centre, P.O. Box 3354, Riyadh 11211, Saudi Arabia.
Int J Hyg Environ Health. 2016 Jul;219(4-5):468-74. doi: 10.1016/j.ijheh.2016.03.002. Epub 2016 Mar 14.
Many studies have highlighted the widespread use of skin-lightening creams containing mercury by women during and after pregnancy to remove dark spots. Women, especially pregnant and lactating mothers using these products are at risk of mercury poisoning because sometimes it has no clinical symptoms, particularly during early exposure. Studies have shown that prenatal and postnatal mercury exposure can cause permanent neurological damage in children. Furthermore, mercury can cause women infertility and birth defects. Even though several studies have examined the reproductive and/or developmental consequences of gestational and lactational mercury exposure from fish consumption and/or dental amalgam, no studies have assessed the possible effects of the long-term use of mercury-containing skin-lightening products by women of childbearing age on their pregnancy outcome and children's health. This commentary aims to collate information on the popular use of mercury-containing skin-lightening creams and sheds the light to the readers about the limitations of the available data on its impact during a prenatal and/or postnatal period. There is an urgent need to assess the adverse health effects of applying these products during pregnancy or lactation on child growth and development through birth cohort studies. Until data from these studies are available, women should be advised not to use topical skin-lightening creams during pregnancy and lactation.
许多研究都强调了怀孕期间和之后女性广泛使用含有汞的美白霜来去除黑斑。由于有时它没有临床症状,尤其是在早期暴露时,使用这些产品的女性,尤其是孕妇和哺乳期母亲,有汞中毒的风险。研究表明,产前和产后接触汞会导致儿童永久性神经损伤。此外,汞会导致女性不孕和出生缺陷。尽管有几项研究检查了从鱼类消费和/或牙合金摄入中接触妊娠期和哺乳期汞对生殖和/或发育的后果,但没有研究评估育龄妇女长期使用含汞美白产品对其妊娠结局和儿童健康的可能影响。这篇评论旨在收集有关含汞美白霜的普及使用的信息,并向读者阐明关于其在产前和/或产后期间影响的现有数据的局限性。迫切需要通过出生队列研究评估在怀孕期间或哺乳期使用这些产品对儿童生长和发育的不良健康影响。在这些研究的数据可用之前,应建议妇女在怀孕期间和哺乳期不要使用外用美白霜。