Hu Chi, West Kevin R, Scherman Oren A
Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.
BP Oil UK Ltd, Whitchurch Hill, Pangbourne, Reading, Berkshire RG8 7QR, UK.
Nanoscale. 2016 Apr 21;8(15):7840-4. doi: 10.1039/c6nr01016d.
The fabrication, characterisation and controlled cargo release of hollow mesoporous raspberry-like colloids (HMRCs), which are assembled by utilising host-guest complexation of cucurbit[8]uril (CB[8]) are described. CB[8] is employed as a supramolecular linker to 'stick' the viologen functionalised paramagnetic iron oxide nanoparticles onto an azobenzene functionalised hollow mesoporous silica core. The formed HMRCs are photoresponsive and can be reversibly disassembled upon light irradiation, endowing them with an ability to release loaded cargo under photocontrol. While the assembled HMRCs retain cargo inside their cavity, disassembled particles with their iron oxide nanoparticle 'caps' removed will release the loaded cargo through the mesoporous shell of the hollow silica colloids. A model system using a boronic acid derivative as the cargo in the HMRCs and Alizarin Red salt as a sensor for the released boronic acid is demonstrated.
本文描述了通过利用葫芦[8]脲（CB[8]）的主客体络合作用组装而成的中空介孔树莓状胶体（HMRCs）的制备、表征及可控的货物释放。CB[8]用作超分子连接体，将紫精功能化的顺磁性氧化铁纳米颗粒“黏附”到偶氮苯功能化的中空介孔二氧化硅核上。所形成的HMRCs具有光响应性，在光照下可发生可逆解离，使其具备在光控下释放负载货物的能力。当组装好的HMRCs将货物保留在其腔内时，去除了氧化铁纳米颗粒“帽”的解离颗粒会通过中空二氧化硅胶体的介孔壳层释放负载的货物。展示了一个模型系统，该系统使用硼酸衍生物作为HMRCs中的货物，并使用茜素红盐作为释放硼酸的传感器。
