Maghsoudi Hemmat, Moradi Sohrab
Department of Surgery, Faculty of Medicine, University of Medical Sciences, Tabriz, Iran ; Sina Hospital, Azadi Street, P.O. Box 1548, Tabriz, 5163639888 East Azarbaijan Iran.
Department of Surgery, Faculty of Medicine, University of Medical Sciences, Tabriz, Iran.
Indian J Surg. 2015 Dec;77(Suppl 3):863-7. doi: 10.1007/s12262-014-1039-0. Epub 2014 Feb 5.
Skin grafts can be used effectively to cover burn injuries. A critical element of this treatment is the adherence of the graft to the wound bed. Honey has been shown to increase the adherence of skin grafts to wound beds and have antibacterial and anti-inflammatory effects and increase healing rate of wounds. We therefore devised a clinical trial to determine the effect of honey on skin graft fixation in burn injuries. Sixty patients were included in this study (in 30 patients, graft was fixed with medical honey, and in 30 patients, it was fixed with dressing or suturing). All patients in two groups were evaluated for infection, graft loss, graft contraction, severity of pain, and need for re-operation. The most common cause of burn was kerosene. Honey significantly decreased infection rate on fifth day and reduced the patient pain. The mean hospital stay was shorter in honey group. Contraction of graft was significantly less in honey group. Honey has strong adhesive properties for skin graft fixation. Medical honey is a natural material, not synthetic. For this reason, we can advise the application of medical honey for the fixation of split thickness skin graft.
皮肤移植可有效用于覆盖烧伤创面。这种治疗方法的一个关键要素是移植皮片与创面床的黏附。研究表明,蜂蜜可增强皮肤移植片与创面床的黏附力,具有抗菌和抗炎作用,并能提高创面愈合速度。因此,我们设计了一项临床试验,以确定蜂蜜对烧伤创面皮肤移植固定的效果。本研究纳入了60例患者(30例患者的移植皮片用医用蜂蜜固定,30例患者的移植皮片用敷料或缝合固定)。对两组所有患者均评估感染情况、移植皮片丢失情况、移植皮片收缩情况、疼痛严重程度及再次手术需求。烧伤的最常见原因是煤油。蜂蜜显著降低了第5天的感染率,并减轻了患者的疼痛。蜂蜜组的平均住院时间较短。蜂蜜组移植皮片的收缩明显较少。蜂蜜对皮肤移植固定具有很强的黏附特性。医用蜂蜜是天然材料,而非合成材料。因此,我们建议应用医用蜂蜜来固定中厚皮片移植。