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蜂蜜与1%磺胺嘧啶银(Ag-SD)用于小儿一度烧伤的处理:比较与对比

Pediatric First-Degree Burn Management With Honey and 1% Silver Sulfadiazine (Ag-SD): Comparison and Contrast.

作者信息

Moniruzzaman Md, Khan Abdur Rahed, Haq Md Ahsanul, Naznin Rawshon Ara, Haque Mainul

机构信息

Pediatric Surgery, 250 Bedded General Hospital, Kushtia, BGD.

Pediatric Surgery, Dhaka Shishu Hospital, Dhaka, BGD.

出版信息

Cureus. 2022 Dec 22;14(12):e32842. doi: 10.7759/cureus.32842. eCollection 2022 Dec.

Abstract

Background The cardinal area of managing fire wounds is guided by adequately evaluating the burn-induced lesion's profundity and size. Superficial second-degree burns are often treated through daily reinstating with fresh sterile bandaging with appropriate topical antimicrobials to allow rapid spontaneous epithelialization. Around the world, a wide variety of substances are used to treat these wounds, from honey to synthetic biological dressings. Objective This study intended to determine honey's therapeutic potential compared with 1% silver sulfadiazine (Ag-SD) in arsenal-caused contusion medicament fulfillment. Methods A total of 70 cases were evaluated in this research work after fulfilling the required selection criteria during the study period of January 2014 to December 2014 and January 2017 to December 2017. Purposive selection criteria were adopted in the study to select research patients. The patients in Group-1 (n = 35) relied on honey as medication, while patients in Group-2 (n = 35) relied on 1% Ag-SD. Results In Group-1, exudation (68.4%) and sloughing (82.9%) were substantially reduced by Days 3 and 5 of therapeutic intervention, respectively. However, in Group-2, a reduction of exudation (17.1%) and sloughing (22.9%) occurred after Days 3 and 5 of treatment, respectively. Completion of the epithelialization process was observed among Group-1 and Group-2 cases. It was detected after Days 7 and 10 of treatment at 36.3% and 77% (Group-1) and 27% and 67% (Group-2), respectively. Around 3 ml of 1% honey was required per body surface area per dressing in Group-1. On the other hand, in Group-2, 2 gm Ag-SD was needed per body surface area per dressing. Conclusion Patients treated with honey found better clinical outcomes in managing superficial partial-thickness burns.

摘要

背景 处理烧伤伤口的关键领域在于充分评估烧伤所致损伤的深度和大小。浅二度烧伤通常通过每日更换新鲜无菌绷带并使用适当的局部抗菌药物来治疗,以实现快速自发上皮化。在世界各地,从蜂蜜到合成生物敷料,各种各样的物质都被用于治疗这些伤口。目的 本研究旨在确定在武器伤药物治疗中,蜂蜜与1%磺胺嘧啶银(Ag-SD)相比的治疗潜力。方法 在2014年1月至2014年12月以及2017年1月至2017年12月的研究期间,在满足所需选择标准后,本研究共评估了70例病例。研究采用目的抽样选择标准来挑选研究患者。第1组(n = 35)的患者使用蜂蜜作为药物,而第2组(n = 35)的患者使用1% Ag-SD。结果 在第1组中,治疗干预第3天和第5天时,渗出(68.4%)和痂皮脱落(82.9%)分别显著减少。然而,在第2组中,治疗第3天和第5天后,渗出(17.1%)和痂皮脱落(22.9%)才分别出现减少。在第1组和第2组病例中均观察到上皮化过程的完成。分别在治疗第7天和第10天后检测到,第1组为36.3%和77%,第2组为27%和67%。第1组每个创面每体表面积大约需要3毫升1%的蜂蜜。另一方面,在第2组中,每个创面每体表面积需要2克Ag-SD。结论 用蜂蜜治疗的患者在处理浅二度烧伤方面取得了更好的临床效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82eb/9779910/252dee92eeeb/cureus-0014-00000032842-i01.jpg

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