Kang Suhai, Chen Fang, Zhong Yan, Han Baiyu, Cheng Guanghe, Guo Aitao, Tian Yuan, Tong Xinyuan, Dou Jingtao, Ye Huiyi
Department of Radiology, Chinese PLA General Hospital, Beijing, China.
Department of Endocrinology, Chinese PLA General Hospital, Beijing, China.
J Clin Hypertens (Greenwich). 2016 Oct;18(10):982-990. doi: 10.1111/jch.12810. Epub 2016 Mar 25.
The aim of this study was to improve the diagnostic efficiency for juxtaglomerular cell tumors (JCTs) and to determine whether clinical and magnetic resonance imaging features can help to differentiate JCTs from clear cell renal cell carcinoma (ccRCC). The clinical features of eight patients with JCTs and 27 patients with ccRCCs were analyzed. A flow diagram for young people with hypertension was applied to facilitate the diagnosis. Clinical presentations were analyzed, including age, hypertension, and hypokalemia. The results of our study produced a flow diagram that narrowed the scope of diagnosis. The statistical results demonstrated that patients with a renal mass aged 14 to 30 years, had grade 3 hypertension, or had moderate hypokalemia had a greater possibility of having a JCT than a ccRCC (P<.0000, P<.01, P<.0005, respectively). In addition, the flow diagram and magnetic resonance imaging features were useful to distinguish JCTs from other renal tumors.
本研究的目的是提高对肾球旁细胞瘤(JCT)的诊断效率,并确定临床和磁共振成像特征是否有助于将JCT与透明细胞肾细胞癌(ccRCC)区分开来。分析了8例JCT患者和27例ccRCC患者的临床特征。应用了针对年轻高血压患者的流程图以促进诊断。分析了临床表现,包括年龄、高血压和低钾血症。我们的研究结果产生了一个缩小诊断范围的流程图。统计结果表明,肾肿块患者年龄在14至30岁、患有3级高血压或中度低钾血症时,患JCT的可能性比ccRCC更大(分别为P<0.0000、P<0.01、P<0.0005)。此外,该流程图和磁共振成像特征有助于将JCT与其他肾肿瘤区分开来。