Schold Jesse D, Elfadawy Nissreen, Buccini Laura D, Goldfarb David A, Flechner Stuart M, P Phelan Michael, Poggio Emilio D
Departments of Quantitative Health Sciences and
Glickman Urological and Kidney Institute, and.
Clin J Am Soc Nephrol. 2016 Apr 7;11(4):674-83. doi: 10.2215/CJN.07950715. Epub 2016 Mar 24.
In 2011, there were approximately 131 million visits to an emergency department in the United States. Emergency department visits have increased over time, far outpacing growth of the general population. There is a paucity of data evaluating emergency department visits among kidney transplant recipients. We sought to evaluate the incidence and risk factors for emergency department visits after initial hospital discharge after transplantation in the United States.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We identified 10,533 kidney transplant recipients from California, New York, and Florida between 2009 and 2012 using the State Inpatient and Emergency Department Databases included in the Healthcare Cost and Utilization Project. We used multivariable Poisson and Cox proportional hazard models to evaluate adjusted incidence rates and time to emergency department visits after transplantation.
There were 17,575 emergency department visits over 13,845 follow-up years (overall rate =126.9/100 patient-years; 95% confidence interval, 125.1 to 128.8). The cumulative incidences of emergency department visits at 1, 12, and 24 months were 12%, 40%, and 57%, respectively, with median time =19 months; 48% of emergency department visits led to hospital admission. Risk factors for higher emergency department rates included younger age, women, black and Hispanic race/ethnicity, public insurance, depression, diabetes, peripheral vascular disease, and emergency department use before transplant. There was wide variation in emergency department visits by individual transplant center (10th percentile =70.0/100 patient-years; median =124.6/100 patient-years; and 90th percentile =187.4/100 patient-years).
The majority of kidney transplant recipients will visit an emergency department in the first 2 years post-transplantation, with significant variation by patient characteristics and individual centers. As such, coordination of care through the emergency department is a critical component of post-transplant management, and specific acumen of transplant-related care is needed among emergency department providers. Additional research assessing best processes of care for post-transplant management and health care expenditures and outcomes associated with emergency department visits for transplant recipients are warranted.
2011年,美国急诊科就诊人次约达1.31亿。随着时间推移,急诊科就诊人次不断增加,远超总人口的增长速度。评估肾移植受者急诊科就诊情况的数据匮乏。我们试图评估美国肾移植受者移植后首次出院后急诊科就诊的发生率及危险因素。
设计、地点、参与者及测量方法:我们利用医疗成本与利用项目中的州住院患者和急诊科数据库,确定了2009年至2012年间来自加利福尼亚州、纽约州和佛罗里达州的10533名肾移植受者。我们使用多变量泊松模型和Cox比例风险模型来评估移植后急诊科就诊的校正发生率及时间。
在13845个随访年中,共有17575次急诊科就诊(总体发生率=126.9/100患者年;95%置信区间为125.1至128.8)。1个月、12个月和24个月时急诊科就诊的累积发生率分别为12%、40%和57%,中位时间为19个月;48%的急诊科就诊导致住院。急诊科就诊率较高的危险因素包括年龄较小、女性、黑人及西班牙裔种族/族裔、公共保险、抑郁症、糖尿病、外周血管疾病以及移植前使用急诊科。各移植中心的急诊科就诊情况差异很大(第10百分位数=70.0/100患者年;中位数=124.6/100患者年;第90百分位数=187.4/100患者年)。
大多数肾移植受者在移植后的头两年会去急诊科就诊,患者特征和各个中心之间存在显著差异。因此,通过急诊科进行护理协调是移植后管理的关键组成部分,急诊科医护人员需要具备移植相关护理的特定敏锐度。有必要进行更多研究,以评估移植后管理的最佳护理流程以及与肾移植受者急诊科就诊相关的医疗保健支出和结果。