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教科书式结局的定义与分析:肾移植中的一种全新质量衡量指标。

Definition and Analysis of Textbook Outcome: A Novel Quality Measure in Kidney Transplantation.

机构信息

Department of Surgery, Duke University Medical Center, Box 3512, Durham, NC, 27710, USA.

Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.

出版信息

World J Surg. 2021 May;45(5):1504-1513. doi: 10.1007/s00268-020-05943-y. Epub 2021 Jan 23.

Abstract

BACKGROUND

"Textbook outcome" (TO) is a novel composite quality measure that encompasses multiple postoperative endpoints, representing the ideal "textbook" hospitalization for complex surgical procedures. We defined TO for kidney transplantation using a cohort from a high-volume institution.

METHODS

Adult patients who underwent isolated kidney transplantation at our institution between 2016 and 2019 were included. TO was defined by clinician consensus at our institution to include freedom from intraoperative complication, postoperative reintervention, 30-day intensive care unit or hospital readmission, length of stay > 75th percentile of kidney transplant patients, 90-day mortality, 30-day acute rejection, delayed graft function, and discharge with a Foley catheter. Recipient, operative, financial characteristics, and post-transplant patient, graft, and rejection-free survival were compared between patients who achieved and failed to achieve TO.

RESULTS

A total of 557 kidney transplant patients were included. Of those, 245 (44%) achieved TO. The most common reasons for TO failure were delayed graft function (N = 157, 50%) and hospital readmission within 30 days (N = 155, 50%); the least common was mortality within 90 days (N = 6, 2%). Patient, graft, and rejection-free survival were significantly improved among patients who achieved TO. On average, patients who achieved TO incurred approximately $50,000 less in total inpatient charges compared to those who failed TO.

CONCLUSIONS

TO in kidney transplantation was associated with favorable post-transplant outcomes and significant cost-savings. TO may offer transplant centers a detailed performance breakdown to identify aspects of perioperative care in need of process improvement.

摘要

背景

“教科书式结局”(TO)是一种新的综合质量衡量标准,涵盖了多个术后终点,代表了复杂手术的理想“教科书式”住院治疗。我们使用来自一家高容量机构的队列为肾移植定义了 TO。

方法

本研究纳入了 2016 年至 2019 年期间在我院接受单纯肾移植的成年患者。TO 由我院临床医生共识定义,包括术中无并发症、术后再次干预、30 天内 ICU 或医院再入院、住院时间超过肾移植患者第 75 百分位数、90 天死亡率、30 天急性排斥反应、延迟移植物功能和出院时带有 Foley 导管。比较达到和未达到 TO 的患者在患者、手术、财务特征以及移植后患者、移植物和无排斥反应的生存方面的差异。

结果

共纳入 557 例肾移植患者。其中,245 例(44%)达到了 TO。TO 失败的最常见原因是延迟移植物功能(N=157,50%)和 30 天内医院再入院(N=155,50%);最不常见的是 90 天内死亡率(N=6,2%)。达到 TO 的患者的患者、移植物和无排斥反应的生存明显改善。平均而言,达到 TO 的患者的总住院费用比未达到 TO 的患者减少了约 50,000 美元。

结论

肾移植中的 TO 与术后转归良好和显著的成本节约相关。TO 可能为移植中心提供详细的绩效分解,以确定需要改进的围手术期护理方面。

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