Blood. 2016 Mar 24;127(12):1519. doi: 10.1182/blood-2016-01-696179.
In this paper, Bertha A. Bouroncle and colleagues describe for the first time the clinical and pathologic features of hairy cell leukemia. The term "leukemic reticuloendotheliosis" proposed a cell of origin that was misplaced, but the remainder of scientific work described is completely consistent with our current understanding of the disease. Specifically, this paper describes the frequency of hairy cell leukemia among all adult leukemias and characterizes the pathology using several techniques still applied today. Furthermore, examining the clinical features of these patients, the authors describe the signs and symptoms of the disease, complications that arise, and expected outcome without modern therapy available today.
在这篇论文中，Bertha A. Bouroncle 及其同事首次描述了毛细胞白血病的临床和病理特征。“白血病性网状内皮增生症”这一术语提出了一个起源错位的细胞，但其余的科学工作描述完全符合我们目前对该疾病的理解。具体来说，本文描述了毛细胞白血病在所有成人白血病中的频率，并使用当今仍在应用的几种技术对其病理学特征进行了描述。此外，作者还通过检查这些患者的临床特征，描述了疾病的体征和症状、出现的并发症以及在没有当今现代疗法的情况下的预期结果。
