Fuchs Cas J, Gonzalez Javier T, Beelen Milou, Cermak Naomi M, Smith Fiona E, Thelwall Pete E, Taylor Roy, Trenell Michael I, Stevenson Emma J, van Loon Luc J C
NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands; Department of Sport, Exercise, and Rehabilitation, Northumbria University, Newcastle upon Tyne, United Kingdom;
Department for Health, University of Bath, Bath, United Kingdom;
J Appl Physiol (1985). 2016 Jun 1;120(11):1328-34. doi: 10.1152/japplphysiol.01023.2015. Epub 2016 Mar 24.
The purpose of this study was to assess the effects of sucrose vs. glucose ingestion on postexercise liver and muscle glycogen repletion. Fifteen well-trained male cyclists completed two test days. Each test day started with glycogen-depleting exercise, followed by 5 h of recovery, during which subjects ingested 1.5 g·kg(-1)·h(-1) sucrose or glucose. Blood was sampled frequently and (13)C magnetic resonance spectroscopy and imaging were employed 0, 120, and 300 min postexercise to determine liver and muscle glycogen concentrations and liver volume. Results were as follows: Postexercise muscle glycogen concentrations increased significantly from 85 ± 27 (SD) vs. 86 ± 35 mmol/l to 140 ± 23 vs. 136 ± 26 mmol/l following sucrose and glucose ingestion, respectively (no differences between treatments: P = 0.673). Postexercise liver glycogen concentrations increased significantly from 183 ± 47 vs. 167 ± 65 mmol/l to 280 ± 72 vs. 234 ± 81 mmol/l following sucrose and glucose ingestion, respectively (time × treatment, P = 0.051). Liver volume increased significantly over the 300-min period after sucrose ingestion only (time × treatment, P = 0.001). As a result, total liver glycogen content increased during postexercise recovery to a greater extent in the sucrose treatment (from 53.6 ± 16.2 to 86.8 ± 29.0 g) compared with the glucose treatment (49.3 ± 25.5 to 65.7 ± 27.1 g; time × treatment, P < 0.001), equating to a 3.4 g/h (95% confidence interval: 1.6-5.1 g/h) greater repletion rate with sucrose vs. glucose ingestion. In conclusion, sucrose ingestion (1.5 g·kg(-1)·h(-1)) further accelerates postexercise liver, but not muscle glycogen repletion compared with glucose ingestion in trained athletes.
本研究的目的是评估摄入蔗糖与葡萄糖对运动后肝脏和肌肉糖原恢复的影响。15名训练有素的男性自行车运动员完成了两个测试日。每个测试日都从糖原消耗运动开始，随后是5小时的恢复时间，在此期间受试者摄入1.5 g·kg⁻¹·h⁻¹的蔗糖或葡萄糖。频繁采集血液样本，并在运动后0、120和300分钟采用¹³C磁共振波谱和成像技术来测定肝脏和肌肉糖原浓度以及肝脏体积。结果如下：运动后摄入蔗糖和葡萄糖后，肌肉糖原浓度分别从85±27（标准差）对86±35 mmol/l显著增加至140±23对136±26 mmol/l（各处理间无差异：P = 0.673）。运动后摄入蔗糖和葡萄糖后，肝脏糖原浓度分别从183±47对167±65 mmol/l显著增加至280±72对234±81 mmol/l（时间×处理，P = 0.051）。仅在摄入蔗糖后的300分钟内肝脏体积显著增加（时间×处理，P = 0.001）。因此，与葡萄糖处理相比（49.3±25.5至65.7±27.1 g；时间×处理，P < 0.001），蔗糖处理在运动后恢复期间肝脏糖原总量增加幅度更大（从53.6±16.2至86.8±29.0 g），这相当于摄入蔗糖与摄入葡萄糖相比，糖原补充率每小时高3.4 g（95%置信区间：1.6 - 5.1 g/h）。总之，在训练有素的运动员中，与摄入葡萄糖相比，摄入蔗糖（1.5 g·kg⁻¹·h⁻¹）可进一步加速运动后肝脏而非肌肉糖原的恢复。
