Patil Prashant P, Midha Samriti, Kumar Sanjeet, Patil Prabhu B
Bacterial Genomics and Evolution Laboratory, Council of Scientific and Industrial Research - Institute of Microbial Technology Chandigarh, India.
Front Microbiol. 2016 Mar 10;7:309. doi: 10.3389/fmicb.2016.00309. eCollection 2016.
Genomic resource of type strains and historically important strains of genus Stenotrophomonas allowed us to reveal the existence of 18 distinct species by applying modern phylogenomic criterions. Apart from Stenotrophomonas maltophilia, S. africana represents another species of clinical importance. Interestingly, Pseudomonas hibsicola, P. beteli, and S. pavani that are of plant origin are closer to S. maltophilia than the majority of the environmental isolates. The genus has an open pan-genome. By providing the case study on genes encoding metallo-β-lactamase and Clustered Regularly Interspaced Short Palindrome Repeats (CRISPR) regions, we have tried to show the importance of this genomic dataset in understanding its ecology.
嗜麦芽窄食单胞菌属模式菌株和具有历史意义的菌株的基因组资源,使我们能够通过应用现代系统发育基因组学标准揭示18个不同物种的存在。除嗜麦芽窄食单胞菌外,非洲嗜麦芽窄食单胞菌是另一个具有临床重要性的物种。有趣的是,源自植物的栖木假单胞菌、槟榔假单胞菌和帕瓦尼嗜麦芽窄食单胞菌比大多数环境分离株更接近嗜麦芽窄食单胞菌。该属具有开放的泛基因组。通过提供关于编码金属β-内酰胺酶的基因和规律成簇间隔短回文重复序列(CRISPR)区域的案例研究,我们试图展示这个基因组数据集在理解其生态学方面的重要性。