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对从墨西哥米却肯州查罗第一地区医院一名感染 COVID-19 的患者身上分离出的一株菌株的基因组进行测序和描述。

Sequencing and description of the genome of a strain of isolated from a patient infected with COVID-19 at Hospital Regional No.1 de Charo, Michoacán, México.

作者信息

Flores-Alvarez Luis Jose, Martínez-Flores Irma, Bustos Patricia, Gómez-García Anel, Gutiérrez-Castellanos Sergio, Poot-Hernández Augusto César, Arredondo-Santoyo Marina

机构信息

Centro de Investigación Biomédica de Michoacán-IMSS. Morelia, Michoacán, México, Mexican Social Security Institute, Mexico City, Mexico City, Mexico.

Centro de Ciencias Genomicas, UNAM. Cuernavaca, Morelos, Universidad Nacional Autónoma de México, Mexico City, Mexico City, Mexico.

出版信息

MicroPubl Biol. 2024 Feb 12;2024. doi: 10.17912/micropub.biology.001051. eCollection 2024.

DOI:10.17912/micropub.biology.001051
PMID:38415072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10897733/
Abstract

is a bacterial genus that can be found in various environments, such as water, soil, and clinical samples. Due to their high genetic and phenotypic diversity, it is difficult to properly identify and classify all isolates. The COVID-19 pandemic caused an increase in nosocomial infections, which played a major role in the high mortality rate among patients in intensive care. This is the first report of the identification of as a nosocomial opportunistic pathogen isolated from a patient with COVID-19. Their genome was isolated, sequenced, and assembled, and it consists of 4,488,090 bp in 24 contigs, 4,103 coding sequences, and a G+C content of 66.58%.

摘要

是一个细菌属,可在各种环境中发现,如水、土壤和临床样本中。由于它们具有高度的遗传和表型多样性,难以对所有分离株进行准确鉴定和分类。新冠疫情导致医院感染增加,这在重症监护患者的高死亡率中起了主要作用。这是首次报告从一名新冠患者中分离出作为医院机会性病原体。对其基因组进行了分离、测序和组装,它由24个重叠群中的4,488,090碱基对组成,有4,103个编码序列,G+C含量为66.58%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc6/10897733/cf695c416af9/25789430-2024-micropub.biology.001051.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc6/10897733/cf695c416af9/25789430-2024-micropub.biology.001051.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc6/10897733/cf695c416af9/25789430-2024-micropub.biology.001051.jpg

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