Tian H E, Ma L, Liu L L, Zhang H, Liu K Y, Zhang Q D, Zhu X Y, Zhu H B
School of Public Health, Southeast University, Nanjing 210009, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2016 Feb 20;34(2):121-3. doi: 10.3760/cma.j.issn.1001-9391.2016.02.011.
To investigate the influence of occupational stress on salivary cortisol concentration in employees.
In September 2014, occupational stress evaluation was performed for 186 employees in a solar photovoltaic company, and enzyme-linked immunosorbent assay was used to measure the salivary cortisol concentration.
The salivary cortisol concentration showed no significant differences between groups with different demographic features(P>0.05). The group with a high score of job control had a significantly lower salivary cortisol concentration than that with a low score(74.62±15.34 μg/L vs 79.95±12.99 μg/L, P<0.05). The groups with high scores of job danger and job responsibility and burden had significantly higher salivary cortisol concentrations than those with low scores(80.29±9.45 μg/L vs 75.60±16.41, P<0.05; 80.94±10.87 μg/L vs 74.05±16.35 μg/L, P<0.05). The salivary cortisol concentration was positively correlated with the scores of job danger and job responsibility and burden(r=0.176 and 0.252, P<0.05) and negatively correlated with the score of job control(r=-0.208, P<0.05).
Salivary cortisol concentration is positively correlated with occupational stress and increases with the increasing degree of occupational stress, and can be used as an objective biomarker for the identification and evaluation of occupational stress.
探讨职业压力对员工唾液皮质醇浓度的影响。
2014年9月，对某太阳能光伏公司186名员工进行职业压力评估，并采用酶联免疫吸附测定法测量唾液皮质醇浓度。
不同人口学特征组间唾液皮质醇浓度差异无统计学意义（P>0.05）。工作控制得分高的组唾液皮质醇浓度显著低于得分低的组（74.62±15.34μg/L对79.95±12.99μg/L，P<0.05）。工作危险性、工作职责与负担得分高的组唾液皮质醇浓度显著高于得分低的组（80.29±9.45μg/L对75.60±16.41，P<0.05；80.94±10.87μg/L对74.05±16.35μg/L，P<0.05）。唾液皮质醇浓度与工作危险性、工作职责与负担得分呈正相关（r=0.176和0.252，P<0.05），与工作控制得分呈负相关（r=-0.208，P<0.05）。
唾液皮质醇浓度与职业压力呈正相关，且随职业压力程度的增加而升高，可作为识别和评估职业压力的客观生物标志物。
