State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, People's Republic of China.
Org Lett. 2016 Apr 15;18(8):1784-7. doi: 10.1021/acs.orglett.6b00447. Epub 2016 Mar 25.
An efficient palladium-catalyzed alkylation of electron-deficient polyfluoroarenes is described. The protocol provides a useful and operationally simple access to a broad scope of alkylated polyfluoroarene derivatives in moderate to excellent yields. This also represents the first example of the introduction of a polyfluoroarene structure involving an alkylpalladium(II) intermediate.
本文描述了一种高效的钯催化缺电子多氟芳烃的烷基化反应。该方法提供了一种有用且操作简单的方法，可在中等至优异的产率下获得广泛的烷基化多氟芳烃衍生物。这也是首例涉及烷基钯（II）中间体的多氟芳烃结构的引入。
