Nielsen Sara Kerstine Kaya, Vangkilde Signe, Wolitzky-Taylor Kate B, Daniel Sarah Ingrid Franksdatter, Hageman Ida
Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
Department of Psychiatry and Biobehavioral Sciences Semel Institute, University of California, California, USA.
BMJ Open. 2016 Mar 25;6(3):e010898. doi: 10.1136/bmjopen-2015-010898.
Cognitive-behavioural therapy (CBT) is effective for treating anxiety disorders and is offered in most mental health services around the world. However, a relatively large number of patients with anxiety disorders do not benefit from CBT, experience relapses or drop out. Reliable predictors of treatment effects are lacking. The aim of this study is to investigate the predictive value of emotion regulation and attentional control for CBT outcome in a routine setting.
In this prospective and practice-based study, 112 patients with anxiety disorders referred for manual-based group CBT at two psychiatric outpatient clinics will be recruited. Emotion regulation, severity of anxiety and attentional control will be assessed with self-report measures and with an experimental computer-based attentional control task at baseline, post-treatment and at a 6-month follow-up. Emotion regulation will be measured with Difficulties in Emotion Regulation Questionnaire, severity of anxiety will be assessed with Beck Anxiety Inventory and attentional control will be measured with the self-report questionnaire, Attention Control Scale, and with an experimental computer-based attentional control task based on theory of visual attention. Data will be analysed using multilevel mixed-effects modelling.
The study is approved by the Danish National Ethical Board, the Department of Psychology Ethical Board, University of Copenhagen and by the Danish Data Protection Agency. Study findings will be disseminated through peer-reviewed journal publications and conference presentations. The Danish Committee System on Health Research Ethics has been notified about the project.
NCT02638363.
认知行为疗法（CBT）在治疗焦虑症方面很有效，且在全球大多数心理健康服务机构中都有提供。然而，有相当数量的焦虑症患者无法从CBT中获益，会经历复发或退出治疗。目前缺乏可靠的治疗效果预测指标。本研究的目的是在常规环境中调查情绪调节和注意力控制对CBT治疗结果的预测价值。
在这项基于实践的前瞻性研究中，将招募112名在两家精神科门诊接受基于手册的团体CBT治疗的焦虑症患者。在基线、治疗后和6个月随访时，将通过自我报告测量以及基于计算机的注意力控制实验任务来评估情绪调节、焦虑严重程度和注意力控制。情绪调节将通过《情绪调节困难问卷》进行测量，焦虑严重程度将通过《贝克焦虑量表》进行评估，注意力控制将通过自我报告问卷《注意力控制量表》以及基于视觉注意理论的计算机注意力控制实验任务进行测量。数据将使用多层次混合效应模型进行分析。
该研究已获得丹麦国家伦理委员会、哥本哈根大学心理学系伦理委员会以及丹麦数据保护局的批准。研究结果将通过同行评审的期刊出版物和会议报告进行传播。已将该项目通知丹麦健康研究伦理委员会系统。
NCT02638363。
