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嗓音治疗对声带息肉的疗效及疗效预测因素

Treatment Efficacy of Voice Therapy for Vocal Fold Polyps and Factors Predictive of Its Efficacy.

作者信息

Lee Yoon Se, Lee Dam Hee, Jeong Go-Eun, Kim Ji Won, Roh Jong-Lyel, Choi Seung-Ho, Kim Sang Yoon, Nam Soon Yuhl

机构信息

Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea..

Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

出版信息

J Voice. 2017 Jan;31(1):120.e9-120.e13. doi: 10.1016/j.jvoice.2016.02.014. Epub 2016 Mar 23.

Abstract

OBJECTIVES

Vocal fold polyps can be treated with either surgical resection or conservative therapy based on voice therapy. This study was designed to analyze the success rate of voice therapy and identify factors that are predictive of the response to this treatment for vocal fold polyps.

METHODS

This was a retrospective cohort study of 92 consecutive patients who were diagnosed with vocal fold polyp(s) and received voice therapy. We divided the patients into responding and non-responding groups. We analyzed clinical and voice parameters related to the voice results.

RESULTS

After voice therapy, 40 patients showed improved findings and did not undergo surgical treatment. By univariate analysis, female patients (54.9%) and small polyps (56.1%) showed a good response to voice therapy. In multivariate analysis, female sex (odds ratio [OR] = 0.34; confidence interval [CI]: 0.14-0.81, P = 0.01) and small size (OR = 0.15; CI: 0.05-0.47, P <0.01) were significantly related to a successful voice response. In small polyps, the sessile type of polyp was found to be related to a good response rate (OR = 0.24; CI: 0.11-0.95, P = 0.04).

CONCLUSIONS

Voice therapy is more effective for small vocal polyps, particularly the sessile type, in female patients.

摘要

目的

声带息肉可通过手术切除或基于嗓音治疗的保守疗法进行治疗。本研究旨在分析嗓音治疗的成功率,并确定可预测声带息肉对该治疗反应的因素。

方法

这是一项对92例连续诊断为声带息肉并接受嗓音治疗的患者进行的回顾性队列研究。我们将患者分为有反应组和无反应组。我们分析了与嗓音结果相关的临床和嗓音参数。

结果

嗓音治疗后,40例患者检查结果改善,未接受手术治疗。单因素分析显示,女性患者(54.9%)和小息肉(56.1%)对嗓音治疗反应良好。多因素分析显示,女性(优势比[OR]=0.34;置信区间[CI]:0.14 - 0.81,P = 0.01)和息肉较小(OR = 0.15;CI:0.05 - 0.47,P <0.01)与嗓音治疗成功反应显著相关。在小息肉中,发现广基型息肉与良好的反应率相关(OR = 0.24;CI:0.11 - 0.95,P = 0.04)。

结论

嗓音治疗对女性患者的小声带息肉,尤其是广基型息肉更有效。

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