Liu Jie, Xiao Cui, Deng Li, Wu Xingdong, Wu Xianwen, Hu Guohua, Yu Lin
Department of Otolaryngology，the First Affiliated Hospital of Chongqing Medical University，Chongqing，400016，China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Feb;35(2):160-163. doi: 10.13201/j.issn.2096-7993.2021.02.015.
The aim of this study is to evaluate the efficacy of CO2 laser and CO2 laser combined with microsuture in the treatment of bilateral sessile polyps of vocal cords. Forty-eight patients with bilateral sessile polyps of vocal cords were randomly divided into CO2 laser group and CO2 laser combined with microsuture group. The surgical effect of each group and the difference between the two groups were evaluated by subjective score and objective voice analysis. One month and three month after operation, Jitter, Shimmer, dysphonia severity index（DSI）, the maximum phonation time（MPT）, the parameters of G and voice handicap index（VHI-10） in the two groups were significantly different from pre-operation（<0.05）. There were also significant differences in Jitter, Shimmer, DSI and MPT between the two groups one month and three month after operation respectively（<0.05）. But no significant differences of the parameters of G and VHI-10 was noted between two groups（>0.05）. The incidence of postoperative vocal cord adhesion was 8.3% and 0 in two groups respectively, and there was no significant difference between the two groups（>0.05）. The CO2 laser combined with microsuturing technique can effectively improve the voice quality of patients with bilateral wide-based vocal cord polyps, and the effect is better than that of using CO2 laser alone.
本研究旨在评估二氧化碳激光及二氧化碳激光联合显微缝合术治疗双侧声带广基息肉的疗效。将48例双侧声带广基息肉患者随机分为二氧化碳激光组和二氧化碳激光联合显微缝合组。通过主观评分和客观嗓音分析评估每组的手术效果及两组间的差异。术后1个月及3个月时，两组的基频微扰（Jitter）、振幅微扰（Shimmer）、嗓音障碍严重指数（DSI）、最长发声时间（MPT）、G参数及嗓音障碍指数（VHI-10）与术前相比均有显著差异（<0.05）。术后1个月及3个月时，两组的Jitter、Shimmer、DSI及MPT也分别有显著差异（<0.05）。但两组的G参数及VHI-10无显著差异（>0.05）。两组术后声带粘连发生率分别为8.3%和0，两组间无显著差异（>0.05）。二氧化碳激光联合显微缝合技术能有效改善双侧广基声带息肉患者的嗓音质量，效果优于单纯使用二氧化碳激光。
