de Moraes C Gustavo, Liebmann Jeffrey M, Medeiros Felipe A, Weinreb Robert N
Bernard and Shirlee Brown Glaucoma Research Laboratory, Edward S. Harkness Eye Institute, Department of Ophthalmology, Columbia University Medical Center, New York, New York, USA.
Bernard and Shirlee Brown Glaucoma Research Laboratory, Edward S. Harkness Eye Institute, Department of Ophthalmology, Columbia University Medical Center, New York, New York, USA.
Surv Ophthalmol. 2016 Sep-Oct;61(5):597-615. doi: 10.1016/j.survophthal.2016.03.006. Epub 2016 Mar 25.
Recent advances in glaucoma diagnosis focus on diagnosing the disease in early stages. Despite the importance of such efforts, a meaningful proportion of patients present in advanced stages. The cost for treatment and monitoring of advanced glaucoma often exceeds that with earlier disease, not to mention the significant effect of visual impairment on quality of life. Moreover, structural and functional tests used to monitor changes encounter technical limitations in advanced cases that can delay detection of true progression. New technologies and methods to analyze longitudinal data may prove helpful for monitoring patients with advanced glaucoma and reduce the burdens of the disease.
青光眼诊断的最新进展集中在疾病的早期诊断上。尽管这些努力很重要，但仍有相当一部分患者在疾病晚期才前来就诊。晚期青光眼的治疗和监测成本往往超过早期疾病，更不用说视力损害对生活质量的重大影响了。此外，用于监测变化的结构和功能测试在晚期病例中存在技术局限性，可能会延迟对真正进展的检测。分析纵向数据的新技术和方法可能有助于监测晚期青光眼患者并减轻疾病负担。
