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一项针对600名孕妇的不安腿综合征前瞻性病例对照问卷调查研究。

A prospective case control questionnaire study for restless leg syndrome on 600 pregnant women.

作者信息

Ozer İrfan, Guzel Işıl, Orhan Gürdal, Erkılınç Selçuk, Öztekin Neşe, Ak Fikri, Taşçı Yasemin

机构信息

a Department of Obstetrics and Gynecology, Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.

b Department of Neurology, Ankara Numune Education and Research Hospital , Ankara , Turkey.

出版信息

J Matern Fetal Neonatal Med. 2017 Dec;30(24):2895-2899. doi: 10.3109/14767058.2016.1170801. Epub 2017 Apr 21.

DOI:10.3109/14767058.2016.1170801
PMID:27019150
Abstract

AIM

To evaluate the clinical characteristics of pregnant women with restless leg syndrome (RLS).

MATERIALS AND METHODS

A total of 600 pregnant women were asked to complete a questionnaire of RLS and medications.

RESULTS

The educational and socio-economical status was significantly lower in study group. The number of patients living in joint family in the study group was statistically higher compared to control group. Hypothyroidism was more frequent in the study group. Calcium and magnesium intake were significantly higher in patients with RLS inversely iron intake was higher in patients without RLS. Lower hemoglobin levels were found to increase the risk of restless leg in pregnancy. Living in a joint family and low educational status were also independent risk factors for restless leg in pregnancy. Iron intake was found to decrease the risk of restless leg. Lower hemoglobin levels were found to be discriminative factor for the presence of RLS. Severity of RLS decreased by iron intake and increased by magnesium intake.

CONCLUSION

Hemoglobin levels, iron intake, living in joint family, educational status are the independent risk factors for restless leg in pregnancy. Lower hemoglobin levels and supplementation of iron are the independent predictors for severity of RLS in pregnant women.

摘要

目的

评估患有不安腿综合征(RLS)的孕妇的临床特征。

材料与方法

共600名孕妇被要求完成一份关于RLS及用药情况的问卷。

结果

研究组的教育程度和社会经济地位显著较低。研究组中生活在联合家庭的患者数量与对照组相比在统计学上更高。研究组甲状腺功能减退更为常见。RLS患者的钙和镁摄入量显著更高,而无RLS患者的铁摄入量更高。发现较低的血红蛋白水平会增加孕期不安腿的风险。生活在联合家庭和低教育程度也是孕期不安腿的独立危险因素。发现铁摄入量会降低不安腿的风险。较低的血红蛋白水平是存在RLS的判别因素。RLS的严重程度因铁摄入量而降低,因镁摄入量而增加。

结论

血红蛋白水平、铁摄入量、生活在联合家庭、教育程度是孕期不安腿的独立危险因素。较低的血红蛋白水平和铁补充是孕妇RLS严重程度的独立预测因素。

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