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皮肤血管周上皮样细胞肿瘤:一种罕见肿瘤的综述

Cutaneous perivascular epithelioid cell tumors: A review on an infrequent neoplasm.

作者信息

Llamas-Velasco Mar, Requena Luis, Mentzel Thomas

机构信息

Mar Llamas-Velasco, Department of Dermatology, Hospital Universitario de La Princesa, 28006 Madrid, Spain.

出版信息

World J Methodol. 2016 Mar 26;6(1):87-92. doi: 10.5662/wjm.v6.i1.87.

Abstract

"Perivascular epithelioid cutaneous" cell tumors (PEComa) are a family of mesenchymal tumors with shared microscopic and immunohistochemical properties: They exhibit both smooth muscle cell and melanocytic differentiation. Non-neoplastic counterpart of PEComa's cells are unknown, as well as the relationship between extracutaneous PEComa and primary cutaneous ones. We will review the clinical setting, histopathologic features, chromosomal abnormalities, differential diagnosis and treatment options for cutaneous PEComa.

摘要

“血管周围上皮样皮肤”细胞肿瘤(PEComa)是一组具有共同微观和免疫组化特性的间叶性肿瘤:它们同时表现出平滑肌细胞和黑素细胞分化。PEComa细胞的非肿瘤对应物尚不清楚,皮肤外PEComa与原发性皮肤PEComa之间的关系也不明确。我们将综述皮肤PEComa的临床情况、组织病理学特征、染色体异常、鉴别诊断及治疗选择。

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本文引用的文献

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Malignant perivascular epithelioid cell tumor: a case report of a cutaneous tumor on the cheek of a male patient.
J Am Acad Dermatol. 2013 Nov;69(5):e262-e264. doi: 10.1016/j.jaad.2013.06.041.

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