Yamshanov V A, Kovan'ko E G, Pustovalov Yu I
Russian Center of Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
Bull Exp Biol Med. 2016 Mar;160(5):712-4. doi: 10.1007/s10517-016-3257-x. Epub 2016 Mar 29.
The effects of amygdaline from apricot kernel added to fodder on the growth of transplanted LYO-1 and Ehrlich carcinoma were studied in mice. Apricot kernels inhibited the growth of both tumors. Apricot kernels, raw and after thermal processing, given 2 days before transplantation produced a pronounced antitumor effect. Heat-processed apricot kernels given in 3 days after transplantation modified the tumor growth and prolonged animal lifespan. Thermal treatment did not considerably reduce the antitumor effect of apricot kernels. It was hypothesized that the antitumor effect of amygdaline on Ehrlich carcinoma and LYO-1 lymphosarcoma was associated with the presence of bacterial genome in the tumor.
研究了饲料中添加杏仁苦苷对小鼠移植性LYO-1和艾氏癌生长的影响。杏仁抑制了两种肿瘤的生长。移植前2天给予生的和热处理后的杏仁产生了显著的抗肿瘤作用。移植后3天给予热处理的杏仁改变了肿瘤生长并延长了动物寿命。热处理并没有显著降低杏仁的抗肿瘤作用。据推测，杏仁苦苷对艾氏癌和LYO-1淋巴肉瘤的抗肿瘤作用与肿瘤中细菌基因组的存在有关。
