Division of Neurology, Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Canada.
UHN-Toronto Western Hospital, Concussion Clinic, 750 Dundas St, West (Med West), Room 3-313, Mailbox no. 2, Toronto, ON, M6J 3S3, Canada.
Curr Neurol Neurosci Rep. 2016 May;16(5):46. doi: 10.1007/s11910-016-0648-3.
Association of repetitive brain trauma with progressive neurological deterioration has been described since the 1920s. Punch drunk syndrome and dementia pugilistica (DP) were introduced first to explain symptoms in boxers, and more recently, chronic traumatic encephalopathy (CTE) has been used to describe a neurodegenerative disease in athletes and military personal with a history of multiple concussions. Although there are many similarities between DP and CTE, a number of key differences are apparent especially when comparing movement impairments. The aim of this review is to compare clinical and pathological aspects of DP and CTE with a focus on disorders of movement.
自 20 世纪 20 年代以来，人们就描述了重复性脑损伤与进行性神经功能恶化之间的关系。拳击手出现的“击醉综合征”和“拳击痴呆症”（DP）首先被用来解释这些症状，最近，慢性创伤性脑病（CTE）被用来描述运动员和有多次脑震荡病史的军事人员的一种神经退行性疾病。尽管 DP 和 CTE 有许多相似之处，但当比较运动障碍时，明显存在一些关键差异。本综述的目的是比较 DP 和 CTE 的临床和病理方面，重点是运动障碍。
