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[高血压母亲所生新生儿的呼吸窘迫以及羊水的蛋白质、脂质和肾脏成熟指数与酶活性]

[Respiratory distress in newborns born to hypertensive mothers and protein, lipid and renal maturity indices and enzymatic activity in the amniotic fluid].

作者信息

Wójcicka-Jagodzińska J, Kuczyńska-Sicińska J, Romejko E, Smolarczyk R, Szczecina R

出版信息

Ginekol Pol. 1989 Oct-Dec;60(10-12):485-8.

PMID:2702191
Abstract

Twenty-five samples obtained by amniocentesis were studied in 25 pregnant women between 35 and 40 weeks of pregnancy with hypertension. The following biochemical investigations were done in the samples: total protein, beta-lipoproteins, cholesterol, uric acid, urea, creatinine, AlAT and AspAT, total alkaline phosphatase and its thermostable isoenzyme, ceruloplasmin and alpha-amylase. The results were analysed in relation to the development of the respiratory distress syndrome in the newborn and were subjected to statistical analysis. In the amniotic fluid of hypertensive mothers in whose children the respiratory distress syndrome developed, reduction was found in the concentrations of beta-lipoproteins and cholesterol. This may have a prognostic significance in the prediction of respiratory distress in early neonatal period.

摘要

对25名怀孕35至40周且患有高血压的孕妇通过羊膜穿刺术获取的25份样本进行了研究。对这些样本进行了以下生化检查:总蛋白、β-脂蛋白、胆固醇、尿酸、尿素、肌酐、谷丙转氨酶和谷草转氨酶、总碱性磷酸酶及其耐热同工酶、铜蓝蛋白和α-淀粉酶。分析了这些结果与新生儿呼吸窘迫综合征发生情况的关系,并进行了统计分析。在其子女发生呼吸窘迫综合征的高血压母亲的羊水中,发现β-脂蛋白和胆固醇浓度降低。这可能对预测新生儿早期呼吸窘迫具有预后意义。

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