Smolarczyk R, Wójcicka-Jagodzińska J, Romejko E, Czajkowski K, Piekarski P, Teliga-Czajkowska J, Kuczyńcka-Sicińska J
II Katedry i Kliniki Połoznictwa i Ginekologii Akademii Medycznej w Warszawie.
Ginekol Pol. 1996 Dec;67(12):593-7.
Sixty two samples of amniotic fluid were submitted to biochemical investigation including 31 samples from women with pregnancy complicated by hypertension (studied group with mean blood pressure 165 +/- 15/95 +/- 5 mmHg) and 31 samples deriving from healthy pregnant women (control group with mean blood pressure 118 +/- 10/74 +/- +/- 9 mmHg). In the studied group pregnancy induced hypertension, primary hypertension and nephrogenic hypertension scored 58%, 32% and 10% of cases respectively. Both investigated and control groups consisted of pregnant women with the same gestational age of 37 +/- 2 weeks (34-40 weeks). The following parameters of amniotic fluid were measured: 1) total protein, 2) albumin, 3) beta-lipoprotein, 4) cholesterol, 5) uric acid, 6) urea, 7) creatinine. Micromethods were used. Amniotic fluid deriving from women with pregnancy complicated by hypertension showed decreased concentrations of total protein, albumin and beta-lipoprotein. In pregnancy complicated by hypertension kidneys of the fetuses were estimated to be as mature as in the normal pregnancy within the same gestational age.
62份羊水样本被送去进行生化检测，其中31份来自患有妊娠合并高血压的女性（研究组，平均血压为165±15/95±5 mmHg），31份来自健康孕妇（对照组，平均血压为118±10/74±9 mmHg）。在研究组中，妊娠高血压、原发性高血压和肾性高血压分别占病例的58%、32%和10%。研究组和对照组均为孕周相同（37±2周，34 - 40周）的孕妇。检测了羊水的以下参数：1）总蛋白，2）白蛋白，3）β-脂蛋白，4）胆固醇，5）尿酸，6）尿素，7）肌酐。采用微量法。来自患有妊娠合并高血压女性的羊水显示总蛋白、白蛋白和β-脂蛋白浓度降低。在妊娠合并高血压的情况下，同一孕周胎儿的肾脏成熟度与正常妊娠时相当。
