Zemlianova M A, Zaitseva N V, Kiritchenko L V
Med Tr Prom Ekol. 2015(12):25-9.
The authors demonstrated that work conditions for main occupations (puncher, cutter, sorter, melter) of titanium-magnesium production are characterized by combined exposure to chemical and physical environmental hazards: titanium oxide aerosol, industrial noise, local vibration, heating microclimate, work hardiness. The work conditions are assessed as hazardous (class 3.2-3.4), work process as hard (class 3.2). The female workers appeared to have reliable increased of AST and prolactine, with lower serum estradiol and FSH levels, if compared to reference group. The workers demonstrated increase in LH, SHBG, prolactine and estradiol, with decrease of free testosterone. That can result in reproductive disorders of men and women, as well as remote effects in offspring.
作者表明，钛镁生产主要职业（冲压工、切割工、分拣工、熔炼工）的工作条件具有化学和物理环境危害综合暴露的特点：氧化钛气溶胶、工业噪声、局部振动、热微气候、工作耐力。工作条件被评估为危险（3.2 - 3.4级），工作过程为艰苦（3.2级）。与对照组相比，女工的谷草转氨酶和催乳素明显升高，血清雌二醇和促卵泡激素水平较低。工人们表现出促黄体生成素、性激素结合球蛋白、催乳素和雌二醇增加，游离睾酮减少。这可能导致男性和女性的生殖障碍，以及对后代的远期影响。
