Myszkowska Dorota, Kubicka Jolanta, Gawlik Jolanta, Obtułowicz Krystyna, Czarnobilska Ewa
Przegl Lek. 2015;72(12):731-5.
Nasal mucosa cytology is an additional examination useful to differentiate chronic rhinitis in allergological and laryngological diagnostics, including chronic sinusitis. The aim of the study was to estimate the cytological picture in a group of patients with the highest percentage of squamous epithelia, suggesting the atrophic rhinitis. The analysis was carried out on the basis of cytological results performed in 3055 patients diagnosed because of chronic rhinitis. Among these patients, in 31 individuals the higher percentage (30% - 76%) of squamous cells was found. In six patients, the clear predominance of squamous cells over ciliated and goblet cells (3:1) was reported. Only in three patients the increased percentage in eosinophils was stressed (3%, 5% and 9% respectively). No basic and metaplastic cells were observed in the studied cytograms. The squamous cells occurred probably as a result of normal mucosa damages during the different inflammatory changes, both allergic and non-allergic, the impact of toxic agents, irritants (including nasal drops). The higher percentage of squamous cells in the nasal cytogram could have explained the low effectiveness of local inflammatory treatment in these patients.
鼻黏膜细胞学检查是变态反应学和喉科学诊断（包括慢性鼻窦炎）中用于鉴别慢性鼻炎的一项辅助检查。本研究的目的是评估一组鳞状上皮细胞比例最高的患者的细胞学特征，提示萎缩性鼻炎。该分析基于对3055例因慢性鼻炎确诊患者的细胞学检查结果进行。在这些患者中，31例发现鳞状细胞比例较高（30% - 76%）。6例患者报告鳞状细胞明显多于纤毛细胞和杯状细胞（3:1）。仅3例患者强调嗜酸性粒细胞百分比增加（分别为3%、5%和9%）。在所研究的细胞涂片未观察到基底细胞和化生细胞。鳞状细胞的出现可能是由于在各种炎症变化（包括变应性和非变应性）、有毒物质、刺激物（包括滴鼻剂）的影响下正常黏膜受损所致。鼻细胞学检查中鳞状细胞比例较高可能解释了这些患者局部炎症治疗效果不佳的原因。
