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脂质性肺炎与结节病。

Lipoid Pneumonia and Sarcoidosis.

作者信息

Glucksman Aaron, Perez Ricardo, Forouhar Faripour A, Burki Nausherwan K

出版信息

Conn Med. 2016 Feb;80(2):91-5.

Abstract

INTRODUCTION

Lipoid pneumonia is a rare, underdiagnosed disorder, and its combined presentation with sarcoidosis is even more unusual.

METHODS

This paper presents a case in which both lipoid pneumonia and sarcoidosis were present, and includes the relevant literature review on lipoid pneumonia.

RESULTS

Lipoid pneumonia may be acute or chronic in its presentation, resulting from exogenous or endogenous factors, or classified as idiopathic, with its precise incidence unknown. Radiographic changes maybe variable, but typically include lower lobe consolidation. Pathologic changes consist of an inflammatory giant cell reaction around lipid-related empty vacuoles and giant cell granulomas. Treatment in the case of exogenous lipoid pneumonia consists of removal of the offending oil ingestion. However, in endogenous lipoid pneumonia, treatment is aimed at the underlying cause, as there is no standard treatment. Repeated bronchoalveolar lavage, corticosteroids, and surgical resection have been used as therapies. The course of the disease is usually not progressive.

摘要

引言

类脂性肺炎是一种罕见的、诊断不足的疾病,其与结节病的合并表现更为罕见。

方法

本文介绍了一例同时存在类脂性肺炎和结节病的病例,并包括了关于类脂性肺炎的相关文献综述。

结果

类脂性肺炎的表现可能为急性或慢性,由外源性或内源性因素引起,或归类为特发性,其确切发病率未知。影像学改变可能多种多样,但通常包括下叶实变。病理改变包括围绕脂质相关空泡的炎性巨细胞反应和巨细胞肉芽肿。外源性类脂性肺炎的治疗包括去除有害的油类摄入。然而,在内源性类脂性肺炎中,由于没有标准治疗方法,治疗针对潜在病因。重复支气管肺泡灌洗、皮质类固醇和手术切除已被用作治疗方法。该病的病程通常不会进展。

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